Zobrazeno 1 - 6
of 6
pro vyhledávání: '"T M, Donohue"'
Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole
Autor:
Paul Fu, Barbara A. French, D. Lucas, A. L. Hagbjork, Samuel W. French, Jun Li, Magnus Ingelman-Sundberg, C. Fang, Z. Q. Gouillon, T. M. Donohue
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 224(4)
The purpose of this investigation was to assess the effect of chlormethiazole treatment on liver damage in the experimental rat intragastric ethanol-feeding model of alcoholic liver disease. Chlormethiazole has been used in the treatment of alcoholic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a886e5f3a964543933f4b140032e7973
https://pubmed.ncbi.nlm.nih.gov/10964266
https://pubmed.ncbi.nlm.nih.gov/10964266
Autor:
Z Q, Gouillon, K, Miyamoto, T M, Donohue, Y J, Wan, B A, French, Y, Nagao, P, Fu, R C, Reitz, A, Hagbjork, C, Yap, Q X, Yuan, M, Ingelman-Sundberg, S W, French
Publikováno v:
Frontiers in bioscience : a journal and virtual library. 4
The ethanol inducible isoform of cytochrome P450, CYP2E1, may play a role in ethanol-induced liver injury. Therefore, the factors which govern CYP2E1 degradation and turnover were investigated. These factors include cAMP, ubiquitin, proteasomal enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::976536fa9743107ed65650ae1e5285b2
https://pubmed.ncbi.nlm.nih.gov/10477671
https://pubmed.ncbi.nlm.nih.gov/10477671
Autor:
Z. Q. Gouillon, K. Miyamoto, C. Yap, Q. X. Yuan, Samuel W. French, T. M. Donohue, Yu-Jui Yvonne Wan, R. C. Reitz, Paul Fu, Barbara A. French, M. Ingelman-Sundberg, A. Hagbjork, Y. Nagao
Publikováno v:
Frontiers in Bioscience. 4:a16
The ethanol inducible isoform of cytochrome P450, CYP2E1, may play a role in ethanol-induced liver injury. Therefore, the factors which govern CYP2E1 degradation and turnover were investigated. These factors include cAMP, ubiquitin, proteasomal enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e062cb1b9ec3ccb4729a1cf0fe36b2ee
https://doi.org/10.2741/gouillon
https://doi.org/10.2741/gouillon
Publikováno v:
Gastroenterology. 84(3)
The effects of chronic ethanol feeding on protein and glycoprotein synthesis and secretion were studied in rat liver slices. Liver slices from rats fed ethanol for 4-5 wk showed a decreased ability to incorporate [14C]glucosamine into medium trichlor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e91b6dc1c2c0f681a1754cb208074ea8
https://pubmed.ncbi.nlm.nih.gov/6822326
https://pubmed.ncbi.nlm.nih.gov/6822326
Publikováno v:
The Journal of laboratory and clinical medicine. 105(1)
Acetaldehyde production and the radiolabeling of hepatic proteins were determined in rat liver slices incubated with 14C-ethanol (10 mmol/L). Significant labeling of hepatic proteins occurred in the presence of protein synthesis inhibitors, indicatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81e00bd672ed2dedf530ad7b4c994680
https://pubmed.ncbi.nlm.nih.gov/3968465
https://pubmed.ncbi.nlm.nih.gov/3968465
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 49(2)
Homogenates of rat liver incubated with 10 mM [14C]ethanol were analyzed for acetaldehyde production and for both stable and unstable radiolabeled acetaldehyde adducts with proteins. During incubation, formation of acetaldehyde and of 14C-labeled pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5f7768ba77e4dc5c7490dea793d1f79
https://pubmed.ncbi.nlm.nih.gov/6876749
https://pubmed.ncbi.nlm.nih.gov/6876749