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Akademický článek

Production of transgenic cattle by somatic cell nuclear transfer (SCNT) with the human granulocyte colony-stimulation factor (hG-CSF)

Autor: Bruno P. Carvalho, Andrielle T. M. Cunha, Bianca D. M. Silva, Regivaldo V. Sousa, Ligiane O. Leme, Margot A. N. Dode, Eduardo O. Melo

Publikováno v: Journal of Animal Science and Technology, Vol 61, Iss 2, Pp 61-68 (2019)

The hG-CSF (human Granulocyte Colony-Stimulating Factor) is a growth and stimulation factor capable of inducing the proliferation of bone marrow cells, several types of leukocytes, among other hematopoietic tissue cells. hG-CSF is used in used to

Externí odkaz: https://doaj.org/article/1e8200df19d24d9b8a79bbb051eb545d

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Colchicine reduces the activation of NLRP3 inflammasome in COVID-19 patients

Publikováno v: Inflammation Research. 72:895-899

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a806600cf9e10df3a2f66bb92f07dd3f
https://doi.org/10.1007/s00011-023-01718-y

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Akademický článek

Bovine epididymal spermatozoa treatment for in vitro fertilization: Heparin accelerates fertilization and enables a reduction in coincubation time.

Autor: Andrielle T M Cunha, José O Carvalho, Ana L S Guimarães, Ligiane O Leme, Felippe M Caixeta, João H M Viana, Margot A N Dode

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0209692 (2019)

This study aimed to establish a protocol for in vitro embryo production using epididymal sperm (EP). Samples were obtained from ejaculated sperm (EJ) and the epididymis of 7 Gir bulls. First, the effect of heparin (+) on the viability, longevity (Exp

Externí odkaz: https://doaj.org/article/c71ecaaae3734cac9921cb7b21f30a6c

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An integer programming model for the selection of pumped-hydro storage projects

Autor: T. Andrade, R. Kelman, T. M. Cunha, L. R. Albuquerque, R. F. Calili

Energy storage systems - in particular, Pumped Hydropower Storage (PHS) - will be increasingly important to support the transition of power systems toward zero emissions. The reason is that PHS can mitigate the variability and uncertainty of renewabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00af09a0b9d044d5b0e8f0a97b26c4f

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Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain

Autor: E U, Carreira, V, Carregaro, M M, Teixeira, A, Moriconi, A, Aramini, W A, Verri, S H, Ferreira, F Q, Cunha, T M, Cunha

Publikováno v: European journal of pain (London, England). 17(5)

Neutrophil recruitment mediated by the CXCL1/KC chemokine and its receptors CXCR1/CXCR2 plays a critical role in inflammatory diseases. Recently, neutrophil migration and activation triggered by CXCL1-CXCR1/2 signalling was implicated in inflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e46dd82cbfc65e100dc402aa0ca7ed69
https://pubmed.ncbi.nlm.nih.gov/23132735

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A crucial role for TNF-alpha in mediating neutrophil influx induced by endogenously generated or exogenous chemokines, KC/CXCL1 and LIX/CXCL5

Autor: S M, Vieira, H P, Lemos, R, Grespan, M H, Napimoga, D, Dal-Secco, A, Freitas, T M, Cunha, W A, Verri, D A, Souza-Junior, M C, Jamur, K S, Fernandes, C, Oliver, J S, Silva, M M, Teixeira, F Q, Cunha

Publikováno v: British journal of pharmacology. 158(3)

Chemokines orchestrate neutrophil recruitment to inflammatory foci. In the present study, we evaluated the participation of three chemokines, KC/CXCL1, MIP-2/CXCL2 and LIX/CXCL5, which are ligands for chemokine receptor 2 (CXCR2), in mediating neutro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49a7210eb1c4bae0bbfe2bfc8298c7c5
https://pubmed.ncbi.nlm.nih.gov/19702783

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Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: role of adenosine acting on A1 receptors

Autor: D A, Valério, F I, Ferreira, T M, Cunha, J C, Alves-Filho, F O, Lima, J R, De Oliveira, S H, Ferreira, F Q, Cunha, R H, Queiroz, W A, Verri

Publikováno v: British journal of pharmacology. 158(2)

D-Fructose-1,6-bisphosphate (FBP) is an intermediate in the glycolytic pathway, exerting pharmacological actions on inflammation by inhibiting cytokine production or interfering with adenosine production. Here, the possible antinociceptive effect of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a9cb5304422c797098793c061179394b
https://pubmed.ncbi.nlm.nih.gov/19645715

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Treatment with DF 2162, a non-competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice

Autor: T M, Cunha, M M, Barsante, A T, Guerrero, W A, Verri, S H, Ferreira, F M, Coelho, R, Bertini, C, Di Giacinto, M, Allegretti, F Q, Cunha, M M, Teixeira

Publikováno v: British journal of pharmacology. 154(2)

Neutrophil migration into tissues is involved in the genesis of inflammatory pain. Here, we addressed the hypothesis that the effect of CXC chemokines on CXCR1/2 is important to induce neutrophil migration and inflammatory hypernociception.Mice were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c27a40f3b92b00ec20b277f71384d1b3
https://pubmed.ncbi.nlm.nih.gov/18362895

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Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain

Autor: E, Ting, A T G, Guerrero, T M, Cunha, W A, Verri, S M, Taylor, T M, Woodruff, F Q, Cunha, S H, Ferreira

Publikováno v: British journal of pharmacology. 153(5)

C5a, a complement activation product, exhibits a broad spectrum of inflammatory activities particularly neutrophil chemoattraction. Herein, the role of C5a in the genesis of inflammatory hypernociception was investigated in rats and mice using the sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::07242850cd81405dd837552e50d1581b
https://pubmed.ncbi.nlm.nih.gov/18084313

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Blockade of the chemokine receptor CXCR2 ameliorates adjuvant-induced arthritis in rats

Autor: M M, Barsante, T M, Cunha, M, Allegretti, F, Cattani, F, Policani, C, Bizzarri, W L, Tafuri, S, Poole, F Q, Cunha, R, Bertini, M M, Teixeira

Publikováno v: British journal of pharmacology. 153(5)

Chemokine receptors CXCR1 and CXCR2 may mediate influx of neutrophils in models of acute and chronic inflammation. The potential benefits of oral administration of a CXCR1/2 inhibitor, DF 2162, in adjuvant-induced polyarthritis (AIA) were investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4337cd8b2de1b81b5f1d5e488aef590c
https://pubmed.ncbi.nlm.nih.gov/17891165

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