Zobrazeno 1 - 10
of 30
pro vyhledávání: '"T M, Badger"'
Autor:
S. G. McLaren, X. C. Shen, G. G. Gao, R. A. Skinner, James Aronson, T. M. Badger, C. K. Lumpkin
Publikováno v:
Journal of Orthopaedic Research. 19:421-427
The effect of age on bone formation in the limb lengthening model of distraction osteogenesis (DO) was investigated in two studies using Sprague-Dawley (SD) rats from two colonies at various ages (CAMM: 9 vs 24 months, Harlan: 4 vs 24 months). Extern
Autor:
D. Ringer, T. M. Badger, S. J. Shema, Martin J. J. Ronis, P. E. Thomas, L. Templer, P. K. Roberson
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 54:101-120
A dose-response study was conducted to examine the growth suppression associated with developmental lead exposure in a rat model and to determine the endocrine mechanisms underlying these effects. Ad libitum intake of lead acetate (0.05% to 0.45% w/v
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(5)
Epidemiological studies have suggested a relationship between diet and colon cancer incidence. Results from animal studies suggest that whey protein, but not casein protein, may provide protective effects against experimentally induced breast cancer
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 295(2)
The CYP3A subfamily is the most abundant of the human hepatic cytochrome P450 enzymes. They mediate the biotransformation of many drugs, including a number of psychotropic, cardiac, analgesic, hormonal, immunosuppressant, antineoplastic, and antihist
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(4)
Consumption of soybean-rich diets is thought to provide significant health benefits such as prevention of cancer, primarily because of the high contents of factors such as the isoflavones genistein and daidzein. Isoflavones circulate and are excreted
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(1)
A study was conducted to determine the protective effects of two common dietary proteins, soy protein isolate (soy) and bovine whey, against chemically induced mammary tumors in female Sprague Dawley rats. Rats were fed AIN-93G diets having casein, s
Publikováno v:
Journal of toxicology and environmental health. Part A. 53(4)
The reproductive, endocrine, and growth effects of developmental lead exposure were assessed using a rat model in which 0.6% lead acetate (w/v) was administered in the drinking water ad libitum during different developmental periods to determine if l
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(3)
The current study was conducted to investigate hormonal regulation of cytochrome P450 2C11 (CYP2C11) in rat liver and kidney of adult male rats. In two experiments, hypophysectomy (Hx) resulted in decreased (P.05) hepatic CYP2C11 apoprotein and mRNA
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(1)
These studies were conducted to determine the effect of hormones on sex-related differences in phencyclidine (PCP) metabolite irreversible binding and to determine the cytochrome P450 isoform(s) involved in this process. Sprague-Dawley male rats were
Autor:
Y, Hu, V, Mishin, I, Johansson, C, von Bahr, A, Cross, M J, Ronis, T M, Badger, M, Ingelman-Sundberg
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 269(3)
Ethanol-inducible cytochrome P450 (CYP) 2E1 (CYP2E1) is responsible for the metabolism of many xenobiotics which exert toxic effects in humans. Specific inhibitors might constitute valuable tools in the elucidation of the pharmacological and toxicolo