PO.2.29 Serum levels of b-cell related factors belonging to the tnf/tnfr superfamily are lower in antiphospholipid-related syndromes than in systemic lupus erythematosus

Autor: S Piantoni, L Andreoli, T Lowin, F Regola, F Franceschini, A Tincani, G Pongratz, S Bertocchi, E Pedretti, S Tamanini

Publikováno v: Lupus Science and Medicine, Vol 9, Iss Suppl 2 (2022)

Externí odkaz: https://doaj.org/article/d563322008aa4677a9f1769e6858316f

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Pro-inflammatory cytokines up-regulate and sensitize metabotropic and ionotropic cannabinoid receptors in rheumatoid arthritis and osteoarthritis synovial fibroblasts

Autor: R.H. Straub, T. Lowin, T. Späth

Publikováno v: 43. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 29. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 25. wissenschaftliche Jahrestagung der Gesellschaft für Kinder-und Jugendrheumatologie (GKJR); 20150902-20150905; Bremen; DOCER.20 /20150901/

Introduction: In collagen-induced arthritis, elevation of endocannabinoid levels improves clinical parameters and decreases synovial inflammation. Joint pain and inflammation are driven by pro-inflammatory cytokines like TNF, which is also involved i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662359d0cd72987b847007768deab13d
http://www.egms.de/en/meetings/dgrh2015/15dgrh074.shtml

RAP-PCR fingerprinting reveals time-dependent expression of matrix-related molecules following stem-cell based TGFβ1-induced chondrocyte development

Autor: M. Nerlich, Ulf Müller-Ladner, P. Angele, J. Schölmerich, T. Lowin, J Schedel, M. Judex, R. Kujat

Publikováno v: International journal of molecular medicine. 27(4)

Different approaches of engineering cartilage to treat defects in the articulating surfaces of the joints have been designed, which mainly use mesenchymal stem cells or autologous chondrocytes for in situ transplantation. However, these cells are poo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c98f1ef95c5278652651d9666ac39eb
https://pubmed.ncbi.nlm.nih.gov/21286661

Expression and function of ghrelin in rheumatoid arthritis

Autor: T. Lowin, C. Mickler, R.H. Straub

Publikováno v: Brain, Behavior, and Immunity. 49:e4

Activation of the immune system in rheumatoid arthritis (RA) is accompanied by perturbations in energy homeostasis. Pro-inflammatory cytokines lead to metabolic changes which results in increased mortality among RA patients. Ghrelin is a gastric horm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75b791fc180e1808769f87c46482688b
https://doi.org/10.1016/j.bbi.2015.06.035