Zobrazeno 1 - 10
of 138
pro vyhledávání: '"T L Delovitch"'
Publikováno v:
Diabetes. 44:614-619
Autor:
U G Danliczyk, T L Delovitch
Publikováno v:
The Journal of Immunology. 153:3533-3542
beta 2-microglobulin (beta 2-m) can regulate the cell surface conformation and expression of a class I MHC H chain. To further determine how the intracellular association of beta 2-m with a class I H chain influences the subsequent cell surface confo
Autor:
A. Krook, Tina Haliotis, S K Anderson, Yu Chun Zhou, T. L. Delovitch, D. T. Denhardt, M. J. Rapoport, Hugh F. Pross
Publikováno v:
Molecular and Cellular Biology. 13:1471-1479
Both p21ras and protein kinase C (PKC) are believed to function downstream of plasma membrane-associated tyrosine kinases in cellular signal transduction pathways. However, it has remained controversial whether they function in the same pathway and,
Publikováno v:
Diabetes. 39:653-656
Publikováno v:
The Journal of Immunology. 144:4147-4155
Cross-linking of B cell surface Ig (sIg) by anti-Ig results in transmembrane signaling. However, the capacity of a thymus-dependent (TD) Ag to mediate B cell signal transduction has been less well documented. Therefore, we examined Ag-induced intrace
Publikováno v:
Autoimmunity. 24:127-129
We would like to provoke discussion on the standardization of experiments involving NOD mice, with a possible view to an international workshop on the subject at a future date.
Publikováno v:
Advances in experimental medicine and biology. 520
Autor:
S, Sharif, T L, Delovitch
Publikováno v:
Archivum immunologiae et therapiae experimentalis. 49
Natural killer T (NKT) cells, which comprise a minor population of T cells in primary and secondary lymphoid organs, possess phenotypic characteristics of both NK and T cells. NKT cells respond to various external stimuli by an early burst of cytokin
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(2)
CD28 costimulation amplifies TCR-dependent signaling in activated T cells, however, the biochemical mechanism(s) by which this occurs is not precisely understood. The small GTPase Rac-1 controls the catalytic activity of the mitogen-activated protein
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(7)
Optimal T cell activation requires two signals, one generated by TCR and another by the CD28 costimulatory receptor. In this study, we investigated the regulation of costimulation-induced mitogen-activated protein kinase (MAPK) activation in primary