Zobrazeno 1 - 10
of 38
pro vyhledávání: '"T L, Goodfriend"'
Digitalis-like factor response to hyperinsulinemia in human pregnancy, a model of insulin resistance
Publikováno v:
Journal of Human Hypertension. 16:851-856
Insulin resistance is strongly associated with hypertension and is postulated to participate in the elevation of blood pressure, although the mechanisms involved are not understood. Recently, we reported that acute increases in plasma insulin levels
Publikováno v:
Experimental Biology and Medicine. 221:32-39
Autor:
M E Elliott, T L Goodfriend
Publikováno v:
Endocrinology. 132:2453-2460
Previous work from this laboratory has suggested that the adrenal glomerulosa is under tonic inhibition by fatty acids. The purpose of the present work was to define the mechanism by which fatty acids inhibit aldosterone synthesis. Experiments with i
Publikováno v:
Endocrinology. 138(6)
Angiotensin II (AngII)-stimulated aldosterone synthesis is mediated by the AngII type 1 (AT1) receptor and requires ongoing protein synthesis. Hormonally-stimulated turnover of a family of 28- to 30-kDa proteins (p30, or steroidogenic acute regulator
Publikováno v:
American journal of hypertension. 7(10 Pt 1)
Separate lines of evidence suggest that abdominal obesity, insulin, and renin are independent risk factors for coronary heart disease. Since insulin levels are higher in abdominally obese subjects and may enhance renin and aldosterone production, the
Publikováno v:
American journal of hospital pharmacy. 48(2)
The costs and potential savings associated with switching patients in a hypertension clinic from enalapril maleate to lisinopril were analyzed. Patients taking enalapril were randomized to receive lisinopril or to continue taking enalapril. For the 4
Autor:
T L Goodfriend
Publikováno v:
Hypertension. 17:139-140
Autor:
T L Goodfriend
Publikováno v:
Academic Medicine. 66:122
Autor:
M E Elliott, T L Goodfriend
Publikováno v:
Proceedings of the National Academy of Sciences. 78:3044-3048
Angiotensin II stimulated 45Ca2+ release from bovine adrenal glomerulosa cells. It also decreased the influx of 45Ca2+ into glomerulosa cells. The effects were observed within 2 min of hormone addition and were blocked by Saralasin a competitive inhi
Autor:
T L Goodfriend, M J Peach
Publikováno v:
Circulation Research. 36:38-48
Evidence is reviewed that three and possibly four peptides formed from renin substrate have biological activity that merits their recognition as agonists. The decepeptide angiotensin I affects sites in the central nervous system and adrenal medulla.