Zobrazeno 1 - 4
of 4
pro vyhledávání: '"T L, Force"'
Autor:
M J, Cross, B R, Berridge, P J M, Clements, L, Cove-Smith, T L, Force, P, Hoffmann, M, Holbrook, A R, Lyon, H R, Mellor, A A, Norris, M, Pirmohamed, J D, Tugwood, J E, Sidaway, B K, Park
Publikováno v:
British journal of pharmacology. 172(4)
The incidence of drug-induced structural cardiotoxicity, which may lead to heart failure, has been recognized in association with the use of anthracycline anti-cancer drugs for many years, but has also been shown to occur following treatment with the
Publikováno v:
Clinical pharmacology and therapeutics. 81(6)
Driven, at least in part, by the National Institutes of Health roadmap, an increasing number of studies has bridged the chasm between observations in the basic research laboratory and the clinical bedside. These studies have been an integral part in
Mitogen regulation of c-Raf-1 protein kinase activity toward mitogen-activated protein kinase-kinase
Publikováno v:
The Journal of biological chemistry. 268(21)
The c-raf-1 protooncogene encodes a Ser/Thr protein kinase. A mitogen-activated protein kinase-kinase (MAPKK) purified from bovine brain is phosphorylated and activated 4-9-fold in vitro by c-Raf-1 from mitogen-treated cells. c-Raf-1 protein kinase a
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 80(4)
The development of coronary ostial stenosis following aortic valve replacement has been attributed to intraoperative trauma to the coronary vessels during continuous coronary perfusion. We describe two patients with this lesion in whom continuous cor