Zobrazeno 1 - 10
of 16
pro vyhledávání: '"T L, Darrow"'
Publikováno v:
The Journal of Immunology. 146:1692-1699
Autologous melanoma-specific CTL recognize a common tumor-associated Ag (TAA) in the context of HLA class I antigens. We have demonstrated that HLA-A2 can be a restricting Ag and, in T cell lines homozygous for HLA-A2, that CTL can be generated by st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e6978e3f98508b7ebd166efc4a71e05
https://doi.org/10.4049/jimmunol.146.5.1692
https://doi.org/10.4049/jimmunol.146.5.1692
Publikováno v:
International journal of cancer. 83(4)
Dendritic cells (DCs) are potent inducers of cytotoxic T lymphocytes (CTLs) when pulsed with an antigenic peptide or tumor lysate. In this report, we have used liposome-mediated gene transfer to examine the ability of plasmid DNA encoding the human m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb1b60af4051fd84e63213e329480a52
https://pubmed.ncbi.nlm.nih.gov/10508491
https://pubmed.ncbi.nlm.nih.gov/10508491
Publikováno v:
Cancer research. 57(8)
Expression of B7.1 costimulatory molecules on tumor cells has been shown to elicit antitumor immunity in mice. In the present study, we have developed a human B7.1 retroviral vector system to effectively transduce human melanoma cell lines and invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::358fb70ebe966ac07f14075439c5cfda
https://pubmed.ncbi.nlm.nih.gov/9108460
https://pubmed.ncbi.nlm.nih.gov/9108460
Autor:
Z, Abdel-Wahab, W P, Li, S, Osanto, T L, Darrow, J, Hessling, C E, Vervaert, M, Burrascano, J, Barber, H F, Seigler
Publikováno v:
Cellular immunology. 159(1)
Human melanoma tumor cells were genetically modified in vitro by transferring the interleukin-2 (IL-2) gene via a retroviral vector into established or fresh tumor cells. In addition, human melanoma cells were transduced in vivo by the direct injecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69b6f6382f55dcec34b50ffbdced63f8
https://pubmed.ncbi.nlm.nih.gov/7954840
https://pubmed.ncbi.nlm.nih.gov/7954840
Autor:
Z A, Abdel-Wahab, S, Osanto, T L, Darrow, J R, Barber, C E, Vervaert, R, Gangavalli, T J, McCallister, H F, Seigler
Publikováno v:
Cancer gene therapy. 1(3)
Human tumor cells transduced with the gamma interferon (gamma IFN) gene are currently used in specific active immunotherapy protocols to enhance the antitumor immune responses of cancer patients. This in vitro study was undertaken to examine the init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9bd0133ac2b23ad2b4ef223630f42fd
https://pubmed.ncbi.nlm.nih.gov/7621248
https://pubmed.ncbi.nlm.nih.gov/7621248
Publikováno v:
Human gene therapy. 5(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e40cac6b337d9a0d5691b95875484a2
https://pubmed.ncbi.nlm.nih.gov/7948138
https://pubmed.ncbi.nlm.nih.gov/7948138
Publikováno v:
Cancer. 69(7)
Tumor-infiltrating lymphocytes (TIL) were isolated from a human melanoma metastatic to the abdomen. The TIL were 99% CD3+ and 99% CD4+ and CD8-. They were dependent on interleukin-2 (IL-2) for growth, as measured in a thymidine uptake assay, and were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c3a7517f19f33afca9bacf30156f0af
https://pubmed.ncbi.nlm.nih.gov/1532342
https://pubmed.ncbi.nlm.nih.gov/1532342
Publikováno v:
Human antibodies and hybridomas. 3(1)
Active specific immunotherapy with irradiated allogeneic melanoma cells has been shown to enhance the humoral immune response in melanoma patients. An increased titer of melanoma-binding antibodies was demonstrated in sera of immunized patients. Lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef402c0d924b2b9f980e0e0b13737cbb
https://pubmed.ncbi.nlm.nih.gov/1576321
https://pubmed.ncbi.nlm.nih.gov/1576321
Publikováno v:
Journal of biological response modifiers. 9(4)
Interactions between the cellular and humoral compartments of the human immune system are well documented. Leukoregulin (LR) is a hormone with the ability to upregulate the natural killer (NK) phenomenon by increasing target cell sensitivity to NK ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc8e9d26fabd7453691cb80f00c56763
https://pubmed.ncbi.nlm.nih.gov/2395004
https://pubmed.ncbi.nlm.nih.gov/2395004
Publikováno v:
Cancer research. 50(3)
Autologous tumor-specific cytotoxic T-lymphocytes (CTLs), generated by repeated stimulation with autologous melanoma and expanded in interleukin 2, are major histocompatibility complex restricted. These CTLs recognize a common tumor-associated antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a76bc4e6576234dfdde5f1b24f496213
https://pubmed.ncbi.nlm.nih.gov/2404572
https://pubmed.ncbi.nlm.nih.gov/2404572