Zobrazeno 1 - 10
of 17
pro vyhledávání: '"T L, Benjamin"'
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 11(5)
Molecular evidence linking polyoma virus to p53 inactivation is thus far lacking, setting this highly oncogenic virus apart from other DNA tumor viruses. As a biological test for interaction, we studied the effects of p53 loss on development of virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99a96ab9562c6c7c6af155b205389089
https://pubmed.ncbi.nlm.nih.gov/10845423
https://pubmed.ncbi.nlm.nih.gov/10845423
Publikováno v:
The American journal of pathology. 141(6)
Alterations in the tumor-inducing ability of a polyoma virus mutant encoding a partially defective middle T oncogene have been investigated. The mutant middle T associates with and activates the tyrosine protein kinase pp60c-src normally but does not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c743b377d0f2e2b0683ad0cff6bc1870
https://pubmed.ncbi.nlm.nih.gov/1334636
https://pubmed.ncbi.nlm.nih.gov/1334636
Publikováno v:
Oncogene. 7(10)
The mouse polyomavirus encodes a tumor-suppressor gene inactivator in its large T protein and a proto-oncogene activator in its middle T protein. We have used site-directed mutagenesis to selectively inactivate the former function without affecting t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf6ebeaa9d0aef02f106e72dc53a6512
https://pubmed.ncbi.nlm.nih.gov/1328987
https://pubmed.ncbi.nlm.nih.gov/1328987
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 2(1)
Expression of antisense c-src RNAs in rat and mouse fibroblasts had a dramatic effect on the function of polyoma virus middle T (mT). Antisense c-src RNA decreased the amount of mT:pp60c-src complexes in de novo virus-infected cells and prevented exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::420078196884c6ce1e3f22ecef8150a7
https://pubmed.ncbi.nlm.nih.gov/1706618
https://pubmed.ncbi.nlm.nih.gov/1706618
Autor:
C J, Dawe, R, Freund, S R, Abromson-Leeman, T W, Dubensky, J, Carroll, M E, Dorf, T L, Benjamin
Publikováno v:
Cancer research. 50
A subset of salivary epithelial tumors induced by mouse polyoma virus (PyV) has been designated lymphoepithelioma on the basis of a prominent lymphocytic component. Serial transplantation of this variant has previously been observed to result in lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e8145ac4ed7a38f45f0083293d4703a
https://pubmed.ncbi.nlm.nih.gov/2167161
https://pubmed.ncbi.nlm.nih.gov/2167161
Publikováno v:
The Journal of Immunology. 128:732-736
As a first step toward identifying papova virus-specific transplantation antigens and characterizing the immune response to these antigens, a series of congenic B10 mouse lines transformed by polyoma virus and SV40 has been obtained. B10.D2 (H-2d) mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8536bb32c94fc701c3927d5ab32d0cf
https://doi.org/10.4049/jimmunol.128.2.732
https://doi.org/10.4049/jimmunol.128.2.732
Publikováno v:
Journal of experimental pathology. 3(2)
In the course of determining tumor profiles for wild-type and recombinant mouse polyoma viruses (MPyV's), we fortuitously discovered two types of necrotizing arterial disease in polyoma tumor-bearing C3H/BiDa mice. One type, designated BLAND, consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cdd1bb86288538dee71f5d238e9908c
https://pubmed.ncbi.nlm.nih.gov/2826731
https://pubmed.ncbi.nlm.nih.gov/2826731
Publikováno v:
The Journal of biological chemistry. 257(21)
Middle T antigen of polyoma virus has an associated tyrosine kinase activity which phosphorylates tyrosine residue 315 on middle T in immunoprecipitates. A peptide representing the sequence of middle T from residue 311 to 319 has been synthesized. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b82b04ef53cc0b83257cedf1a0d19ea7
https://pubmed.ncbi.nlm.nih.gov/6290466
https://pubmed.ncbi.nlm.nih.gov/6290466
Publikováno v:
Virology. 167(2)
The PTA strain of polyomavirus induces a variety of epithelial as well as mesenchymal tumors at high frequencies, while the RA strain induces only rare mesenchymal tumors following inoculation into newborn mice. DNA sequence analysis has revealed one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf8399f2454cbc145748aaff2028b522
https://pubmed.ncbi.nlm.nih.gov/2849243
https://pubmed.ncbi.nlm.nih.gov/2849243
Publikováno v:
The Journal of biological chemistry. 264(15)
The transforming protein of polyoma virus, middle T antigen, associates with two cellular enzymes, pp60c-src, a protein tyrosine kinase, and a phosphatidylinositol kinase that forms phosphatidylinositol 3-phosphate. The formation of a ternary complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf32c9dbce392242235f686f2873099f
https://pubmed.ncbi.nlm.nih.gov/2542286
https://pubmed.ncbi.nlm.nih.gov/2542286