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of 35
pro vyhledávání: '"T Kwaku Dayie"'
Autor:
Susmita Roy, Heiko Lammert, Ryan L Hayes, Bin Chen, Regan LeBlanc, T Kwaku Dayie, José N Onuchic, Karissa Y Sanbonmatsu
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 3, p e1005406 (2017)
Our 13C- and 1H-chemical exchange saturation transfer (CEST) experiments previously revealed a dynamic exchange between partially closed and open conformations of the SAM-II riboswitch in the absence of ligand. Here, all-atom structure-based molecula
Externí odkaz:
https://doaj.org/article/8ab6a05fea3742f2b2caaf5cc33b1883
Autor:
Kehinde M. Taiwo, Lukasz T. Olenginski, Felix Nußbaumer, Hyeyeon Nam, Stefan Hilber, Christoph Kreutz, T. Kwaku Dayie
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 153:293-299
Several isotope-labeling strategies have been developed for the study of RNA by nuclear magnetic resonance (NMR) spectroscopy. Here, we report a combined chemical and enzymatic synthesis of [7-15N]-guanosine-5′-triphosphates for incorporation into
Autor:
Kehinde M, Taiwo, Lukasz T, Olenginski, Felix, Nußbaumer, Hyeyeon, Nam, Stefan, Hilber, Christoph, Kreutz, T Kwaku, Dayie
Publikováno v:
Monatshefte fur chemie. 153(3)
Several isotope-labeling strategies have been developed for the study of RNA by nuclear magnetic resonance (NMR) spectroscopy. Here, we report a combined chemical and enzymatic synthesis of [7-The online version contains supplementary material availa
Akademický článek
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Publikováno v:
Science Advances
19F-13C spy couple enables NMR visualization of long-lived signals of large RNA structures, folds, and drug binding pockets.
RNAs form critical components of biological processes implicated in human diseases, making them attractive for small-mol
RNAs form critical components of biological processes implicated in human diseases, making them attractive for small-mol
Publikováno v:
Methods. 103:11-17
Even though Nuclear Magnetic Resonance (NMR) spectroscopy is one of the few techniques capable of determining atomic resolution structures of RNA, it is constrained by two major problems of chemical shift overlap of resonances and rapid signal loss d
Publikováno v:
Angewandte Chemie. 128:2774-2777
Conformational equilibria are increasingly recognized as pivotal for biological function. Traditional structural analyses provide a static image of conformers in solution that sometimes present conflicting views. From (13) C and (1) H chemical exchan
Autor:
Christoph Kreutz, Andrew P. Longhini, Bin Chen, Jonathan D. Dinman, Felix Nußbaumer, T. Kwaku Dayie
Publikováno v:
Chemistry
Conformational dynamics of RNA molecules play a critical role in governing their biological functions. Measurements of RNA dynamic behavior sheds important light on sites that interact with their binding partners or cellular stimulators. However, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564b2ac272cc9d8ce5e94cfb8fed1e50
https://europepmc.org/articles/PMC7640883/
https://europepmc.org/articles/PMC7640883/
Publikováno v:
Mol. BioSyst.. 10:384-390
C-di-GMP has emerged as a ubiquitous second messenger, which regulates the transition between sessile and motile lifestyles and virulence factor expression in many pathogenic bacteria using both RNA riboswitches and protein effectors. We recently sho
Publikováno v:
Methods in enzymology. 565
Knowledge of how ribonucleic acid (RNA) structures fold to form intricate, three-dimensional structures has provided fundamental insights into understanding the biological functions of RNA. Nuclear magnetic resonance (NMR) spectroscopy is a particula