Zobrazeno 1 - 10
of 25
pro vyhledávání: '"T Katherine Tamai"'
Autor:
T Katherine Tamai, Yusuke Nakane, Wataru Ota, Akane Kobayashi, Masateru Ishiguro, Naoya Kadofusa, Keisuke Ikegami, Kazuhiro Yagita, Yasufumi Shigeyoshi, Masaki Sudo, Taeko Nishiwaki‐Ohkawa, Ayato Sato, Takashi Yoshimura
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 5, Pp n/a-n/a (2018)
Abstract Chronic circadian disruption due to shift work or frequent travel across time zones leads to jet‐lag and an increased risk of diabetes, cardiovascular disease, and cancer. The development of new pharmaceuticals to treat circadian disorders
Externí odkaz:
https://doaj.org/article/c7bdc79576a34ebc8a8689479d3981bc
Autor:
Mike J Downey, Danuta M Jeziorska, Sascha Ott, T Katherine Tamai, Georgy Koentges, Keith W Vance, Till Bretschneider
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e27886 (2011)
The extraction of fluorescence time course data is a major bottleneck in high-throughput live-cell microscopy. Here we present an extendible framework based on the open-source image analysis software ImageJ, which aims in particular at analyzing the
Externí odkaz:
https://doaj.org/article/986f69cff5644414add7b98f87a58b61
Autor:
Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonid V. Ivanov, Thomas F. Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher S. Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang
Publikováno v:
Neuron. 110(20)
Brain tissue transcriptomes may be organized into gene coexpression networks, but their underlying biological drivers remain incompletely understood. Here, we undertook a large-scale transcriptomic study using 508 wild-type mouse striatal tissue samp
Autor:
Ayato Sato, Jiachen Shen, Andrew S. I. Loudon, Naoyuki Yamamoto, Akiko Shimada, Toshiya Nishimura, Toshitaka Nabeshima, Naoya Kadofusa, Kei Nakayama, Souta Minou, Minoru Tanaka, Nobuyuki Shiina, Tomoya Nakayama, Ai Shinomiya, Takashi Yoshimura, Ying-Jey Guh, Yuki Okushi, Taeko Nishiwaki-Ohkawa, Yusuke Nakane, Tsuyoshi Shimmura, T. Katherine Tamai, Yuko Furukawa, Kousuke Okimura
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance At high latitudes, about 10% of the population suffers from depression in winter. Although it has become a serious public health issue, its underlying mechanism remains unknown. Interestingly, animals also show depression-like behavior i
Autor:
Kazuki Fukumoto, P. Lynne Howell, Gerben van Ooijen, Ryoichiro Kageyama, Mayu Yamano, T. Katherine Tamai, Christin Rakers, Kumiko Yoshioka-Kobayashi, Diego A. Golombek, Rika Kojima, Takuya Matsuo, Ralf Stanewsky, Kensuke Kaneko, Hideaki Kakeya, Maria Luísa Jabbur, Carl Hirschie Johnson, Melisa L. Lamberti, Stephanie Tammam, David Whitmore, Hitoshi Okamura, Jean-Michel Fustin, Yao Xu, Ellen Grünewald, Samantha J. Cargill, Shiqi Ye, Marijke Versteven
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-1 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-1 (2020)
The methyl cycle is a universal metabolic pathway providing methyl groups for the methylation of nuclei acids and proteins, regulating all aspects of cellular physiology. We have previously shown that methyl cycle inhibition in mammals strongly affec
Autor:
Hitoshi Okamura, Jean-Michel Fustin, David Whitmore, Ellen Grünewald, Ryoichiro Kageyama, Maria Luísa Jabbur, Stephanie Tammam, Samantha J. Cargill, Marijke Versteven, Carl Hirschie Johnson, Melisa L. Lamberti, Christin Rakers, Kumiko Yoshioka-Kobayashi, P. Lynne Howell, Gerben van Ooijen, Diego A. Golombek, Takuya Matsuo, Rika Kojima, Ralf Stanewsky, Kensuke Kaneko, Kazuki Fukumoto, Shiqi Ye, Hideaki Kakeya, Yao Xu, Mayu Yamano, T. Katherine Tamai
Publikováno v:
Fustin, J-M, Ye, S, Rakers, C, Kaneko, K, Fukumoto, K, Yamano, M, Versteven, M, Grünewald, E, Cargill, S J, Tamai, T K, Xu, Y, Jabbur, M L, Kojima, R, Lamberti, M L, Yoshioka-Kobayashi, K, Whitmore, D, Tammam, S, Howell, P L, Kageyama, R, Matsuo, T, Stanewsky, R, Golombek, D A, Johnson, C H, Kakeya, H, Ooijen, G V & Okamura, H 2020, ' Methylation deficiency disrupts biological rhythms from bacteria to humans ', Communications Biology, vol. 3, no. 1, 211 . https://doi.org/10.1038/s42003-020-0942-0
Communications Biology
Fustin, J-M, Ye, S, Rakers, C, Kaneko, K, Fukumoto, K, Yamano, M, Versteven, M, Grunewald, E, Cargill, S, Tamai, T K, Xu, Y, Jabbur, M L, Kojima, R, Lamberti, M L, Yoshioka Kobayashi, K, Whitmore, D, Tammam, S, Howell, P L, Kageyama, R, Matsuo, T, Stanewsky, R, Golombek, D A, Johnson, C H, Kakeya, H, Van Ooijen, G & Okamura, H 2020, ' Methylation deficiency disrupts biological rhythms from bacteria to humans ', Communications biology, vol. 3, no. 1, 211 . https://doi.org/10.1038/s42003-020-0942-0
Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)
Communications Biology
Fustin, J-M, Ye, S, Rakers, C, Kaneko, K, Fukumoto, K, Yamano, M, Versteven, M, Grunewald, E, Cargill, S, Tamai, T K, Xu, Y, Jabbur, M L, Kojima, R, Lamberti, M L, Yoshioka Kobayashi, K, Whitmore, D, Tammam, S, Howell, P L, Kageyama, R, Matsuo, T, Stanewsky, R, Golombek, D A, Johnson, C H, Kakeya, H, Van Ooijen, G & Okamura, H 2020, ' Methylation deficiency disrupts biological rhythms from bacteria to humans ', Communications biology, vol. 3, no. 1, 211 . https://doi.org/10.1038/s42003-020-0942-0
Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)
The methyl cycle is a universal metabolic pathway providing methyl groups for the methylation of nuclei acids and proteins, regulating all aspects of cellular physiology. We have previously shown that methyl cycle inhibition in mammals strongly affec
Publikováno v:
Journal of Biological Rhythms
Studies from a number of model systems have shown that the circadian clock controls expression of key cell cycle checkpoints, thus providing permissive or inhibitory windows in which specific cell cycle events can occur. However, a major question rem
Autor:
Marijke Versteven, Yao Xu, Maria Luísa Jabbur, Hitoshi Okamura, Jean-Michel Fustin, T. Katherine Tamai, Ralf Stanewsky, Diego A. Golombek, Melisa L. Lamberti, David Whitmore, Ryoichiro Kageyama, Shiqi Ye, Gerben van Ooijen, Rika Kojima, Christin Rakers, Kumiko Yoshioka-Kobayashi, Takuya Matsuo, Samantha J. Cargill, Carl Hirschie Johnson
The methyl cycle is a universally conserved metabolic pathway operating in prokaryotes and eukaryotes. In this pathway, the amino acid methionine is used to synthesize S-adenosylmethionine, the methyl donor co-substrate in the methylation of nucleic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548e4f2bc5d7e293e06b3bd602fdb1c6
Autor:
Takashi Yoshimura, Yasufumi Shigeyoshi, Ayato Sato, Keisuke Ikegami, T. Katherine Tamai, Taeko Nishiwaki-Ohkawa, Wataru Ota, Yusuke Nakane, Kazuhiro Yagita, Masaki Sudo, Naoya Kadofusa, Akane Kobayashi, Masateru Ishiguro
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 5, Pp n/a-n/a (2018)
EMBO Molecular Medicine
EMBO Molecular Medicine
Chronic circadian disruption due to shift work or frequent travel across time zones leads to jet‐lag and an increased risk of diabetes, cardiovascular disease, and cancer. The development of new pharmaceuticals to treat circadian disorders, however
Autor:
Tsuyoshi Hirota, May Hui, David A. Prober, Suna Li, Eric A. Mosser, Steve A. Kay, Chanpreet Singh, Amy Wang, Andrew Giovanni, Cindy N. Chiu, T. Katherine Tamai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
The circadian clock ensures that behavioral and physiological processes occur at appropriate times during the 24-hour day/night cycle, and is regulated at both the cellular and organismal levels. To identify pathways acting on intact animals, we perf