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Akademický článek

Residue-specific N-terminal glycine to aldehyde transformation renders analytically pure single-site labeled proteins.

Autor: Sahu, Tularam, Kumar, Mohan, T. K., Sajeev, Joshi, Manas, Mishra, Ram Kumar, Rai, Vishal

Publikováno v: Chemical Communications; 11/18/2022, Vol. 58 Issue 89, p12451-12454, 4p

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Amphiphilic Small-Molecule Assemblies to Enhance the Solubility and Stability of Hydrophobic Drugs

Autor: Ram Kumar Mishra, Yogesh M. Gangarde, Nihar R. Panigrahi, Ishu Saraogi, T K Sajeev

Publikováno v: ACS Omega, Vol 5, Iss 43, Pp 28375-28381 (2020)
ACS Omega

Amphiphilic assemblies made from diverse synthetic building blocks are well known for their biomedical applications. Here, we report the synthesis of gemini-type amphiphilic molecules that form stable assemblies in water. The assembly property of mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60e0392d4df4208cdeff9f8b1bac3fa
https://doi.org/10.1021/acsomega.0c04395

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A single amino acid Gly-tag enables metal-free protein purification

Autor: Vishal Rai, Surya Dev Mishra, T K Sajeev, Neelesh C Reddy, Landa Purushottam, V B Unnikrishnan, Mansi Gujrati, Ram Kumar Mishra, Dattatraya Gautam Rawale, Srinivasa Rao Adusumalli

Publikováno v: Chemical Science

Analytically pure proteins are indispensable for diverse applications, including therapeutics. Here, we report a methodology where a single amino acid, glycine, enables metal-free protein purification. This robust platform is enabled by a Gly-tag res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4042ae20a3ee20ff4e107af36e8eea9c
https://doi.org/10.1039/d0sc01153c

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