Zobrazeno 1 - 10
of 190
pro vyhledávání: '"T K, Sampath"'
Autor:
T K Sampath, Jenneke Klein Nulend, Elisabeth H. Burger, M.N. Helder, S.C. Dieudonné, S. W. Goei, Slobodan Vukicevic, C.M. Semeins
Publikováno v:
Journal of Bone and Mineral Research. 9:771-780
Osteogenic protein-1 (OP-1, also called BMP-7) is a bone morphogenetic member of the TGF-beta superfamily. In the present study, we examined the effect of recombinant human OP-1 on cartilage and bone formation in organ cultures of metatarsal long bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d8252bda4789410dc5ae10ad87c94f
https://doi.org/10.1002/jbmr.5650090603
https://doi.org/10.1002/jbmr.5650090603
Autor:
Mislav Jelić, Don Jin, Vanja Bašić, Nikolina Bašić, Susan Ryan, Haimanti Dorai, J. Maliakal, B. Dattatreyamurty, Ana Stavljenić, Alyssa A. Shepard, Dunja Rogić, Denise Griffiths, T. K. Sampath, Mei-Shu Shih, Slobodan Vukicevic, W. Jones, M. Pastorcic
Publikováno v:
Journal of Clinical Investigation. 102:202-214
We have shown that osteogenic protein-1 (OP-1) (bone morphogenetic protein-7) is responsible for the induction of nephrogenic mesenchyme during embryonic kidney development. Gene knock-out studies showed that OP-1 null mutant mice die of renal failur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9fbf7880c1ef8462db0cff75f7fc442
https://doi.org/10.1172/jci2237
https://doi.org/10.1172/jci2237
Autor:
Kohsuke Takeda, Masao Takase, Hidenori Ichijo, T. K. Sampath, Masahiro Kawabata, Kohei Miyazono, Takeshi Imamura
Publikováno v:
Biochemical and Biophysical Research Communications. 244:26-29
Members of the transforming growth factor-beta (TGF-beta) superfamily transduce signals via Smad proteins. Smad2 and Smad3 mediate TGF-beta signaling, whereas Smad1 and Smad5 transduce bone morphogenetic protein (BMP) signals. Smad4 is a common media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26631ad306cbe4dbd047fc3426170cf
https://doi.org/10.1006/bbrc.1998.8200
https://doi.org/10.1006/bbrc.1998.8200
Publikováno v:
Molecular Endocrinology. 11:1832-1845
Bone morphogenetic proteins induce chondrogenesis and osteogenesis in vivo. To investigate molecular mechanisms involved in chondrocyte induction, we examined the effect of osteogenic protein (OP)-1/bone morphogenetic protein-7 on the collagen X prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470e7d64583cdbe61eb16312ee5e503f
https://doi.org/10.1210/mend.11.12.0022
https://doi.org/10.1210/mend.11.12.0022
Autor:
Donna D. Strong, Subburaman Mohan, T. K. Sampath, David J. Baylink, J. M. Hayden, David R. Powell
Publikováno v:
Endocrinology. 138:4240-4247
To begin delineating molecular mechanisms by which osteogenic protein-1 (OP-1) modulates its effect on the insulin-like growth factor (IGF) system in human skeletal cells, we evaluated time-course effects of OP-1 on the expression of IGFBP-3 messenge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::445c773abb3dc0714ee640a733015050
https://doi.org/10.1210/endo.138.10.5457
https://doi.org/10.1210/endo.138.10.5457
Autor:
Yasuhiro Ishidou, Hiroki Yoshida, N. Origuchi, Kyouji Hayashi, Takeshi Imamura, K. Yonemori, T. K. Sampath, P. ten Dijke, T. Nagamine, Mitsuyasu Kato, Shingo Maeda, Takashi Sakou
Publikováno v:
Bone. 21:23-30
To clarify the pathogenesis of ossification of the ligamentum flavum (OLF), we examined the expression and localization of bone morphogenetic proteins (BMPs) and their receptors (BMPRs) in the ligamentum flavum of the patients with OLF by immunohisto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a0b47c064f470ee7ba258df5f2b86d
https://doi.org/10.1016/s8756-3282(97)00080-x
https://doi.org/10.1016/s8756-3282(97)00080-x
Autor:
C H Heldin, Hideomi Yamashita, Kohei Miyazono, T. K. Sampath, Mitsuyasu Kato, Keiko Funa, Naoshi Yamada, P. ten Dijke
Publikováno v:
British Journal of Cancer
The distribution of bone morphogenetic protein (BMP) type I receptors and the activin type I receptor (ActR-I) was investigated in 16 cases of human glioma and five cases of non-tumourous gliosis tissue by immunohistochemical technique. Both BMP type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f82346aef40e6085089f85e7f24be0
http://europepmc.org/articles/PMC2074358
http://europepmc.org/articles/PMC2074358
Autor:
Hidetoshi Yamashita, Kohei Miyazono, T. K. Sampath, C H Heldin, Danny Huylebroeck, James C. Smith, P. ten Dijke, M Andries
Publikováno v:
The Journal of Cell Biology
Proteins in the TGF-beta superfamily transduce their effects through binding to type I and type II serine/threonine kinase receptors. Osteogenic protein-1 (OP-1, also known as bone morphogenetic protein-7 or BMP-7), a member of the TGF-beta superfami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d32770c7bb3ab55552e523747d18053
http://europepmc.org/articles/PMC2120513
http://europepmc.org/articles/PMC2120513
Autor:
T. K. Sampath, Hidetoshi Yamashita, Hidenori Ichijo, D.L. Riddle, C H Heldin, P. ten Dijke, Kohei Miyazono, A. H. Reddi, M. Estevez
Publikováno v:
Scopus-Elsevier
Bone morphogenetic proteins (BMPs) are multifunctional proteins, structurally related to transforming growth factor-beta (TGF-beta) and activin. TGF-beta and activin exert their effects by forming heteromeric complexes of type I and type II serine/th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52e26656eab6e37a5859badc37e97a4
https://doi.org/10.1016/s0021-9258(17)32506-1
https://doi.org/10.1016/s0021-9258(17)32506-1
Publikováno v:
Growth Factors. 11:227-234
We recently showed that osteogenic protein-1(OP-1), a bone morphogenetic protein member of TGF-beta superfamily, induces endochondral bone formation in vivo, and stimulates growth and differentiation of osteoblasts in rat calvarial-derived cell cultu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4364d401af122e6295825123ad8bffd8
https://doi.org/10.3109/08977199409046920
https://doi.org/10.3109/08977199409046920