Zobrazeno 1 - 10 of 68 pro vyhledávání: '"T Jeroen N Hiltermann"'
1
Akademický článek
Chronic Obstructive Pulmonary Disease Is Not Associated with KRAS Mutations in Non-Small Cell Lung Cancer.
Autor: Ali Saber, Anthonie J van der Wekken, Gerald S M A Kerner, Maarten van den Berge, Wim Timens, Ed Schuuring, Arja ter Elst, Anke van den Berg, T Jeroen N Hiltermann, Harry J M Groen
Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0152317 (2016)
Mutations in epithelial growth factor receptor (EGFR), as well as in the EGFR downstream target KRAS are frequently observed in non-small cell lung cancer (NSCLC). Chronic obstructive pulmonary disease (COPD), an independent risk factor for developin
Externí odkaz: https://doaj.org/article/b4ecc89ed86a46e888a658a37e48a5e3
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2
Akademický článek
Genomic Aberrations in Crizotinib Resistant Lung Adenocarcinoma Samples Identified by Transcriptome Sequencing.
Autor: Ali Saber, Anthonie J van der Wekken, Klaas Kok, M Martijn Terpstra, Lisette J Bosman, Mirjam F Mastik, Wim Timens, Ed Schuuring, T Jeroen N Hiltermann, Harry J M Groen, Anke van den Berg
Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0153065 (2016)
ALK-break positive non-small cell lung cancer (NSCLC) patients initially respond to crizotinib, but resistance occurs inevitably. In this study we aimed to identify fusion genes in crizotinib resistant tumor samples. Re-biopsies of three patients wer
Externí odkaz: https://doaj.org/article/37c8f74ccc624e1a8995de7aac96a923
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3
Akademický článek
mRNA-1273 vaccination induces polyfunctional memory CD4 and CD8 T cell responses in patients with solid cancers undergoing immunotherapy or/and chemotherapy
Autor: Anastasia Gangaev, Yannick van Sleen, Nicole Brandhorst, Kelly Hoefakker, Bimal Prajapati, Amrita Singh, Annemarie Boerma, Marieke van der Heiden, Sjoukje F. Oosting, Astrid A. M. van der Veldt, T. Jeroen N. Hiltermann, Corine H. GeurtsvanKessel, Anne-Marie C. Dingemans, Egbert F. Smit, Elisabeth G. E. de Vries, John B. A. G. Haanen, Pia Kvistborg, Debbie van Baarle
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionResearch has confirmed the safety and comparable seroconversion rates following SARS-CoV-2 vaccination in patients with solid cancers. However, the impact of cancer treatment on vaccine-induced T cell responses remains poorly understood.M
Externí odkaz: https://doaj.org/article/80fab91389fd443aa2a12002abce5698
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4
Akademický článek
Randomised controlled trial of first-line tyrosine-kinase inhibitor (TKI) versus intercalated TKI with chemotherapy for EGFR-mutated nonsmall cell lung cancer
Autor: Rolof G.P. Gijtenbeek, Vincent van der Noort, Joachim G.J.V. Aerts, Jeske A. Staal-van den Brekel, Egbert F. Smit, Frans H. Krouwels, Frank A. Wilschut, T. Jeroen N. Hiltermann, Wim Timens, Ed Schuuring, Joost D.J. Janssen, Martijn Goosens, Paul M. van den Berg, A. Joop de Langen, Jos A. Stigt, Ben E.E.M. van den Borne, Harry J.M. Groen, Wouter H. van Geffen, Anthonie J. van der Wekken
Publikováno v: ERJ Open Research, Vol 8, Iss 4 (2022)
Introduction Previous studies have shown interference between epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors and chemotherapy in the cell cycle, thus reducing efficacy. In this randomised controlled trial we investigated whether i
Externí odkaz: https://doaj.org/article/7a4d1f9500d043fca5a9dd6a08afeeba
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5
Akademický článek
Circulating tumor cells in advanced non-small cell lung cancer patients are associated with worse tumor response to checkpoint inhibitors
Autor: Menno Tamminga, Sanne de Wit, T. Jeroen N. Hiltermann, Wim Timens, Ed Schuuring, Leon W. M. M. Terstappen, Harry J. M. Groen
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Background Non-small cell lung cancer (NSCLC) patients treated with checkpoint inhibitors show long lasting responses, but it is hard to predict which patients will profit from this treatment with the currently used marker, programmed death
Externí odkaz: https://doaj.org/article/9a8b54e897394e67804a2f24e72d16a9
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6
Akademický článek
Lack of Conventional Acinar Cells in Parotid Salivary Gland of Patient Taking an Anti-PD-L1 Immune Checkpoint Inhibitor
Autor: Sarah Pringle, Bert van der Vegt, Xiaoyan Wang, Nico van Bakelen, T. Jeroen N. Hiltermann, Fred K. L. Spijkervet, Arjan Vissink, Frans G. M. Kroese, Hendrika Bootsma
Publikováno v: Frontiers in Oncology, Vol 10 (2020)
Background: Salivary glands (SGs) can be damaged by immune checkpoint inhibitor (ICI) therapy. In patients with ICI-induced SG dysfunction, 60% progress to fulfill classification criteria for primary Sjögren's syndrome (pSS), owing to immune foci in
Externí odkaz: https://doaj.org/article/18fc0c184d6044a989b0ea1af47b9109
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7
Akademický článek
Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity
Autor: Daan van den Broek, T. Jeroen N. Hiltermann, Bonne Biesma, Winand N. M. Dinjens, Nils A. 't Hart, John W. J. Hinrichs, Mathie P. G. Leers, Kim Monkhorst, Matthijs van Oosterhout, Volkher Scharnhorst, Ed Schuuring, Ernst-Jan M. Speel, Michel M. van den Heuvel, Ron H. N. van Schaik, Jan von der Thüsen, Stefan M. Willems, Leonie de Visser, Marjolijn J. L. Ligtenberg
Publikováno v: Frontiers in Oncology, Vol 9 (2020)
The diagnostic landscape of non-small cell lung cancer (NSCLC) is changing rapidly with the availability of novel treatments. Despite high-level healthcare in the Netherlands, not all patients with NSCLC are tested with the currently relevant predict
Externí odkaz: https://doaj.org/article/690a5016a3c44acc879bb9a893ae5eb8
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8
The additional diagnostic value of virtual bronchoscopy navigation in patients with pulmonary nodules: The NAVIGATOR study
Autor: Birgitta I. Hiddinga, Dirk-Jan Slebos, T. David Koster, Lucie B.M. Hijmering-Kappelle, T. Jeroen N. Hiltermann, Hanneke Kievit, Anthonie J. van der Wekken, Gonda de Jonge, Rozemarijn Vliegenthart, Caroline Van De Wauwer, Wim Timens, Frederike Bensch
Publikováno v: Lung Cancer, 177, 37-43. ELSEVIER IRELAND LTD
BACKGROUND: The number of solitary pulmonary nodules to be evaluated is expected to increase and therefore we need to improve diagnostic and therapeutic tools to approach these nodules. To prevent patients from futile invasive procedures and receivin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d063f50cc8768f34f047b6479e00b86e
https://research.rug.nl/en/publications/c710261a-20ff-4a0e-bec6-cb452ec6d8b7
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9
Leukapheresis increases circulating tumour cell yield in non-small cell lung cancer, counts related to tumour response and survival
Autor: Kiki C. Andree, Menno Tamminga, Harry J.M. Groen, T. Jeroen N. Hiltermann, Ed Schuuring, Leon W.M.M. Terstappen, Anouk Mentink, Hilda van den Bos, Peter M. Lansdorp, Wim Timens, Diana C.J. Spierings
Publikováno v: British journal of cancer, 126, 409-418. Nature Publishing Group
Br J Cancer
British Journal of Cancer, 126. Nature Publishing Group
BACKGROUND: Circulating tumour cells (CTCs) can be used to monitor cancer longitudinally, but their use in non-small cell lung cancer (NSCLC) is limited due to low numbers in the peripheral blood. Through diagnostic leukapheresis (DLA) CTCs can be ob
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5b1a37695c590ab520b4a7d0c1d879
http://www.scopus.com/inward/record.url?scp=85120319054&partnerID=8YFLogxK
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