Zobrazeno 1 - 10
of 12
pro vyhledávání: '"T J Sprinkle"'
Publikováno v:
Journal of Biological Chemistry. 265:11849-11853
2',3'-Cyclic nucleotide-3'-phosphodiesterase (CNP1 and CNP2 with Mr of 46,000 and 48,000, respectively) is the major enzyme of central nervous system myelin. It is associated with oligodendroglial plasma membrane and uncompacted myelin (myelin-like f
Publikováno v:
Neuropathology and applied neurobiology. 20(3)
We have carried out immunocytochemical reactions using antibodies to markers of oligodendrocytes, astrocytes, microglia and proliferating cells (PCNA) in sections of human brain in a variety of demyelinating conditions and human immunodeficiency viru
Autor:
T D, Anderson, A, Davidovich, D, Feldman, T J, Sprinkle, J, Arezzo, C, Brosnan, R O, Calderon, L H, Fossom, J T, DeVries, G H, DeVries
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 70(5)
The reverse transcriptase inhibitor, 2',3'-dideoxycytidine (ddC), causes a dose-limiting peripheral neuropathy in humans, the mechanism of which is unknown. Rabbits given ddC develop peripheral myelinopathy and axonopathy, but it has not been determi
Publikováno v:
The Journal of biological chemistry. 265(20)
2',3'-Cyclic nucleotide-3'-phosphodiesterase (CNP1 and CNP2 with Mr of 46,000 and 48,000, respectively) is the major enzyme of central nervous system myelin. It is associated with oligodendroglial plasma membrane and uncompacted myelin (myelin-like f
Autor:
T. J. Sprinkle, Owen M. Rennert
Publikováno v:
Journal of Neurochemistry. 26:499-504
— Sulfated galactocerebroside synthesis was examined in vitro in mouse spinal cord cultures. This system permitted the study of the effects of phenylketonuric metabolites upon synthesis of a specific myelin component, sulfatide, formed early in pos
Publikováno v:
Analytical Biochemistry. 88:449-456
This paper describes a new, sensitive, and reproducible method for the determination of 2′,3′-cyclic-nucleotide 3′-phosphodiesterase (EC 3.1.4.37) activity in both central and peripheral nervous system tissue, as well as in extraneural tissue.
Publikováno v:
Journal of neuroscience research. 13(3)
Bovine cerebrum, including the corpus callosum, and a human oligodendroglioma were investigated by an immunohistochemical technique to determine the distribution of 2':3'-cyclic nucleotide 3'-phosphodiesterase (CNP). Also, three human oligodendroglio
Publikováno v:
Brain research. 426(2)
Monoclonal antibodies against human and bovine 2':3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) were generated by fusing FOX-NY myeloma cells with spleen cells from RBF/Dn mice previously immunized with the purified brain antigens. The enzyme is
Autor:
T J, Sprinkle
Publikováno v:
Critical reviews in neurobiology. 4(3)
2',3'-Cyclic nucleotide 3'-phosphohydrolase (E.C. 3.1.4.37; CNPase) is a myelin-associated enzyme. In central and peripheral nervous system tissues, the enzyme is localized almost exclusively in the two cell types that elaborate myelin, the oligodend
Publikováno v:
Journal of neurochemistry. 30(2)
— 2′,3′-Cyclic-nucleotide-3′-phosphodiesterase activity was examined in several regions of rat brain during development, namely optic nerve, olfactory bulb, cerebrum, cerebellum, midbrain, brain stem, and spinal cord. From 4 to 120 days the t