Zobrazeno 1 - 10
of 16
pro vyhledávání: '"T J O'Rourke"'
Autor:
Donald P. Quick, T. J. O'Rourke, James R. Faulkner, Mark J. Noble, Geoffrey R. Weiss, Stephen R. Smalley, Ronald L. Stephens, Ian M. Thompson, E. David Crawford, Gregory P. Swanson
Publikováno v:
Journal of Urology. 176:548-553
Radiation is considered the standard treatment for locally advanced (T3 and T4) prostate cancer but cure with radiation alone is infrequent. Studies have shown that adding androgen ablation improves the results but there is still much room for improv
Autor:
Ahmad Awada, J. G. Kuhn, E Raymond, T. J. O'Rourke, W Lynch, Susanne King, J Brentzel, D. D. Von Hoff, T. D. Brown, Howard A. Burris
Publikováno v:
Investigational New Drugs. 16:19-27
Brequinar (DUP 785; NSC 368390) is a quinoline carboxylic acid derivative that inhibits pyrimidine synthesis at the level of dihydro-orotate dehydrogenase and revealed synergy with cisplatin in preclinical models. In this study investigating the phar
Autor:
John S. Macdonald, T. J. O'Rourke, Thomas R. Fleming, Phyllis J. Goodman, Pugh Rp, Thomas D. Brown
Publikováno v:
Anti-Cancer Drugs. 6:219-223
Trimetrexate (TMQ), a non-classical folate antagonist, was studied in a randomized controlled trial in patients with advanced colorectal cancer and without prior chemotherapy. Patients were randomly assigned to one of three treatments: TMQ at 200 mg/
Autor:
J. Hardy, J. Eckhardt, G. Rodriguez, D. D. Von Hoff, G. R. Weiss, T. J. O'Rourke, John G Kuhn, P. New, Howard A. Burris, S. Fields, G. M. Clark
Publikováno v:
Anti-Cancer Drugs. 5:520-526
Ormaplatin is a platinum analog that was developed because of an altered toxicity profile and non-cross resistance to cisplatin in both in vitro and in vivo models. To determine the toxicities and maximum tolerated dose of ormaplatin on a daily times
Autor:
Craig Smith, K A Konkol, K C Abbott, T J O'Rourke, M Ristic, C J Holland, C K McAllister, S J Vukelja
Publikováno v:
American Journal of Hematology. 38:230-234
A 67-year-old white man with human ehrlichiosis infection complicated by pancytopenia, hemophagocytic syndrome, disseminated intravascular coagulopathy and septic shock is presented. The patient had been on a three-week camping trip to California, Co
Publikováno v:
American journal of hematology. 51(2)
Essential thrombocythemia (ET) is an uncommon myeloproliferative disorder, which is thought to develop from a multipotent stem cell. Like other myeloproliferative diseases, ET is associated with an increased risk of development of acute leukemia (AL)
Publikováno v:
Cancer. 70(6)
Testicular relapse (TR) in adult acute myelogenous leukemia (AML) is uncommon, occurring in only 1-2% of patients with bone marrow relapse. TR in the absence of systemic relapse has been reported previously in 2 adults and 12 children, of which 67% w
Autor:
T. S. Jackson, T. J. O‘Rourke
Publikováno v:
54th EAEG Meeting.
Timing and character mismatches between borehole and surface seismic are often encountered when correlating and calibrating seismic data. Even after block shifts are applied, a good match at shallow depths can gradually deteriorate into a mis-tie of
Autor:
John S. Macdonald, T. J. O'Rourke, Thomas R. Fleming, Phyllis J. Goodman, Ellen R. Gaynor, Thomas D. Brown, Sarah A. Taylor, John R. Neefe
Publikováno v:
Journal of immunotherapy : official journal of the Society for Biological Therapy. 10(5)
Fifty evaluable patients with advanced colorectal cancer, but without prior chemotherapy or immunotherapy, were randomized to one of two schedules of recombinant gamma-interferon (rGIFN). Twenty-four evaluable patients received rGIFN as a 2-h intrave
Autor:
W. G. Satterlee, K. Havlin, T. D. Brown, Howard A. Burris, T. J. O'Rourke, D. D. Von Hoff, John G. Kuhn, P. G. Tarassoff, J. B. Craig
Publikováno v:
European Journal of Cancer. 30:417-418