Zobrazeno 1 - 10
of 17
pro vyhledávání: '"T J McCown"'
There is high comorbidity between post-traumatic stress disorder (PTSD) and alcohol dependence, indicating that exposure to stressful events increases the risk of alcoholism. Thus, identifying pharmacological targets with potential therapeutic value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a7274eea8dca9d9b292c83187e6ad49
https://doi.org/10.21236/ada594088
https://doi.org/10.21236/ada594088
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(3)
Although previous in vivo electrophysiological studies demonstrated a consistent ethanol enhancement of gamma-aminobutyric acid (GABA) responsiveness from substantia nigra reticulata (SNR) neurons, ethanol applied in vitro to dissociated neurons from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2d69118d35d04b75319e3d9c02c4f76
https://pubmed.ncbi.nlm.nih.gov/10565824
https://pubmed.ncbi.nlm.nih.gov/10565824
Publikováno v:
Gene Therapy. 20:465-465
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::752d9dca268462bb2d548ae14c805120
https://doi.org/10.1038/gt.2013.11
https://doi.org/10.1038/gt.2013.11
Autor:
H E, Criswell, P E, Simson, D J, Knapp, L L, Devaud, T J, McCown, G E, Duncan, A L, Morrow, G R, Breese
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(1)
Previous investigations have suggested a relationship between zolpidem binding within specific brain regions and the ability of ethanol or zolpidem to enhance gamma-aminobutyric acid (GABA)-induced inhibition. The purpose of the present study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1deed70c594bb759cc143ebe13420dc7
https://pubmed.ncbi.nlm.nih.gov/7714808
https://pubmed.ncbi.nlm.nih.gov/7714808
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(1)
The present investigation provides evidence that there is neuroanatomical specificity for ethanol enhancement of gamma-aminobutyric acid (GABA)-induced inhibition in mammalian brain and that the expression of a specific GABAA isoreceptor is associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2970ab5f6461fe47ca85045555fa589
https://pubmed.ncbi.nlm.nih.gov/8229784
https://pubmed.ncbi.nlm.nih.gov/8229784
Publikováno v:
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. 2
The studies described will demonstrate that the subunit composition of a GABAA receptor allows ethanol to enhance responses to GABA. Since we have determined that ethanol will influence responses to glycine, nicotine and NMDA in some, but not all, ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a8e9ed2a42090d9eca71fb9252b7de2
https://pubmed.ncbi.nlm.nih.gov/7538301
https://pubmed.ncbi.nlm.nih.gov/7538301
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 237(2)
The role of the inferior colliculus and GABAeric transmission within this structure in the development of susceptibility to sound-induced seizures in ethanol-dependent rats was examined. Ethanol-dependent rats with bilateral electrolytic lesions whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::676424ceffbb09aa31eca3ddea575feb
https://pubmed.ncbi.nlm.nih.gov/3009788
https://pubmed.ncbi.nlm.nih.gov/3009788
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 231(2)
Administration of L-dopa or apomorphine to neonatal and adult 6-hydroxydopamine (6-OHDA)-treated rats resulted in different behavioral responses depending on the age at which dopaminergic fibers were destroyed. When neonatal 6-OHDA-treated rats were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e450b578a7ae13d890ca996c5499e149
https://pubmed.ncbi.nlm.nih.gov/6149306
https://pubmed.ncbi.nlm.nih.gov/6149306
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 224(3)
Induction of anesthesia with pentobarbital (40 mg/kg), urethane (1.8 g/kg), chloral hydrate (400 mg/kg) or ketamine (150 mg/kg) followed by a 20-min sham implantation of a bipolar electrode in substantia nigra fibers caused a marked, ipsilateral incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34c2b7ac6c16a931aa2ad75db7f97ed8
https://pubmed.ncbi.nlm.nih.gov/6827473
https://pubmed.ncbi.nlm.nih.gov/6827473
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 238(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a18593019a6e70264bebc4a8756ef3b8
https://pubmed.ncbi.nlm.nih.gov/3598897
https://pubmed.ncbi.nlm.nih.gov/3598897