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IL-1 beta maturation: evidence that mature cytokine formation can be induced specifically by nigericin

Autor: D Perregaux, J Barberia, A J Lanzetti, K F Geoghegan, T J Carty, C A Gabel

Publikováno v: The Journal of Immunology. 149:1294-1303

Mouse peritoneal macrophages stimulated with LPS produce large amounts of pro-IL-1 beta. When these cells were pulse-labeled with [35S]methionine, however, little labeled cytokine appeared in the medium after a chase, and that which was externalized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14d98473f6dcc568857535822a320195
https://doi.org/10.4049/jimmunol.149.4.1294

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Inhibition of 5-lipoxygenase product formation and polymorphonuclear cell degranulation by tenidap sodium in patients with rheumatoid arthritis

Autor: Louis W. Heck, Leland D. Loose, T. J. Carty, Warren D. Blackburn, James D. Eskra

Publikováno v: Arthritis & Rheumatism. 34:204-210

We studied the effect of tenidap sodium, a new antiinflammatory/antirheumatic drug (120 mg/day for 7 days), on eicosanoid production and neutrophil degranulation in patients with rheumatoid arthritis. Endogenous prostaglandin E2 levels and ex vivo pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa03b1b29b7170b85d8a9235c2b9b9a
https://doi.org/10.1002/art.1780340212

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Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans

Autor: S Uden, T J Carty, P. J. Barnes, Kian Fan Chung, J D Eskra, B J O'Connor

Publikováno v: Scopus-Elsevier

Inhaled PAF provokes bronchoconstriction, causes peripheral blood neutropenia with rebound neutrophilia, and generates urinary production of the bronchoconstrictor eicosanoids, thromboxane (TX)A2, and the cysteinyl leukotrienes. We examined the effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f17a082fd29090a3df854970080ed62d
https://pubmed.ncbi.nlm.nih.gov/8025768

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IL-1 beta maturation: evidence that mature cytokine formation can be induced specifically by nigericin

Autor: D, Perregaux, J, Barberia, A J, Lanzetti, K F, Geoghegan, T J, Carty, C A, Gabel

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 149(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90af2d86b1b966373194355848270513
https://pubmed.ncbi.nlm.nih.gov/1500719

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Pyridoxal phosphate-dependent conformational states of glycogen phosphorylase as probed by interconverting enzymes

Autor: G W Tessmer, Donald J. Graves, T J Carty, J R Skuster, Gerald M. Carlson, R F Parrish

Publikováno v: Journal of Biological Chemistry. 250:2254-2258

The interaction between pyridoxal 5'-phosphate and the convertible serine of glycogen phosphorylase has been investigated by using: specific interconverting enzymes, phosphorylase kinase and phosphorylase phosphatase; effectors, glucose and glucose 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::147faf491dc0ed48aa7a00e721803771
https://doi.org/10.1016/s0021-9258(19)41710-9

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Regulation of glycogen phosphorylase. Role of the peptide region surrounding the phosphoserine residue in determining enzyme properties

Autor: Tu J-I, T J Carty, D J Graves

Publikováno v: Journal of Biological Chemistry. 250:4980-4985

A phosphopeptide which contains 14 residues including phosphoserine and which is derived from the NH2-terminal region of skeletal muscle glycogen phosphorylase (Nolan, C., Novoa, W. B., Krebs, E. G., and Fischer, E. H. (1964) Biochemistry 3, 542-551)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be3e690cdd30ffee4407cf7358741b06
https://doi.org/10.1016/s0021-9258(19)41265-9

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