Zobrazeno 1 - 10
of 32
pro vyhledávání: '"T J Bucci"'
Publikováno v:
Drug and Chemical Toxicology. 21:97-117
Controversy regarding the use of ad libitum feeding in chronic rodent toxicity studies will soon result in issue of a FDA Points to Consider document. Caloric intakes are now recognized to be important uncontrolled variables in bioassays because rode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f8141b066af086c2c0bf60890afbb1
https://doi.org/10.3109/01480549809017854
https://doi.org/10.3109/01480549809017854
Autor:
T. J. Bucci, P. C. Howard
Publikováno v:
Journal of Toxicology: Toxin Reviews. 15:293-302
Fumonisins are mycotoxins produced worldwide by Fusarium fungi, principally F. moniliforme. While this fungus can be cultured from virtually all harvested corn, fumonisin production is highly variable. Fumonisin ingestion induces a number of fatal di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e7c7dc0ff5f870ee9e1a540fae647fc
https://doi.org/10.3109/15569549609016449
https://doi.org/10.3109/15569549609016449
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 45(2)
Although, diet restriction (DR) has been shown to substantially increase longevity while reducing or delaying the onset of age-related diseases, little is known about the mechanisms underlying the beneficial effects of DR on acute toxic outcomes. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab04a07c3696d000b1655a7e4fcea20c
https://pubmed.ncbi.nlm.nih.gov/9848130
https://pubmed.ncbi.nlm.nih.gov/9848130
Publikováno v:
Advances in experimental medicine and biology. 392
Fumonisin B1 is a mycotoxin produced by Fusarium moniliforme, a fungus that infects corn and other grains in the U.S. Fumonisin ingestion causes a variety of effects including equine leukoencephalomalacia and porcine pulmonary edema, and has been ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d791e3077fd65fa9047f1858ef76961e
https://pubmed.ncbi.nlm.nih.gov/8850621
https://pubmed.ncbi.nlm.nih.gov/8850621
Publikováno v:
Laboratory animal science. 45(5)
We allocated 110 DBA/2NNia mice of either sex to one of two feeding regimens: ad libitum (AL) or food restriction (FR) to 60% of the amount consumed by the AL group. The mice were examined at 3, 6, 9, 12, 18, and 24 months (at 3 months, only AL mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2efa909e50e7ef2d3aea15008edf6018
https://pubmed.ncbi.nlm.nih.gov/8569148
https://pubmed.ncbi.nlm.nih.gov/8569148
Publikováno v:
Hepatology (Baltimore, Md.). 21(2)
Acetaminophen (APAP) is a widely used analgesic and antipyretic drug that causes massive centrilobular hepatic necrosis at high doses, leading to death. The objectives of this study were to test our working hypothesis that preplaced cell division and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f34ab9edf2e89683acb152ec494970a
https://pubmed.ncbi.nlm.nih.gov/7843722
https://pubmed.ncbi.nlm.nih.gov/7843722
Publikováno v:
Veterinary and human toxicology. 36(2)
We evaluated the response of mink to oral administration of the oxidant compound propylene glycol (PG) to better understand the relative susceptibility of mink red blood cells (RBC) to oxidant injury. Feeding a diet containing 12% PG to 6 mink for 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c41786ea34c0bdae3f90f1a683cfdd2d
https://pubmed.ncbi.nlm.nih.gov/8197707
https://pubmed.ncbi.nlm.nih.gov/8197707
Autor:
D W, Roberts, T J, Bucci, R W, Benson, A R, Warbritton, T A, McRae, N R, Pumford, J A, Hinson
Publikováno v:
The American journal of pathology. 138(2)
Acetaminophen overdose causes severe hepatotoxicity in humans and laboratory animals, presumably by metabolism to N-acetyl-p-benzoquinone imine: and binding to cysteine groups as 3-(cystein-S-yl)acetaminophen-protein adduct. Antiserum specific for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc182a2f698a117445394ab616f3326e
https://pubmed.ncbi.nlm.nih.gov/1992763
https://pubmed.ncbi.nlm.nih.gov/1992763
Publikováno v:
Veterinary Pathology. 25:286-296
Hepatoblastomas from B6C3F1 and BALB/c mice were examined by light and electron microscopy and by immunohistochemical reactions for alpha-fetoprotein, keratin, and vimentin. Tumors occurred in one group of a chronic bioassay for the interaction of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5a4ee0b68e27784f405d1b20ba8b0c
https://doi.org/10.1177/030098588802500407
https://doi.org/10.1177/030098588802500407
Publikováno v:
Experimental Biology and Medicine. 155:124-127
SummaryThe distribution of vitamin A in the kidney was investigated autoradi-ographically. Three hours after intravenous administration of [11, 12-3H]retinyl acetate to vitamin A-deficient rats, the vast majority of the label was present in cells of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8c1c7744551262713886b7b10c1d54
https://doi.org/10.3181/00379727-155-39758
https://doi.org/10.3181/00379727-155-39758