Biochemical Methods for the Characterization of Influenza Viruses with Reduced Sensitivity to 4-Guanidino-Neu5Ac2en

Autor: R C, Bethell, G J, Hart, T J, Blick, A, Sahasrabudhe, J L, McKimm-Breschkin

Publikováno v: Methods in molecular medicine. 24

Viruses that are less sensitive to the influenza neuraminidase (NA)-specific inhibitor 4-guanidino-Neu5Ac2en (zanamavir) (1) can be isolated after several passages in MDCK cells in the presence of the inhibitor. Although there are three reports of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8f6495ae648ce8df7c4a53a18d88979
https://pubmed.ncbi.nlm.nih.gov/21331923

Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en

Autor: A Sahasrabudhe, T. Tiong, T J Blick, Jennifer L. McKimm-Breschkin, G J Hart, R C Bethell, D Marshall, C R Penn

Publikováno v: Scopus-Elsevier

The compounds 4-amino-Neu5Ac2en (5-acetylamino-2,6-anhydro-4-amino-3,4,5- trideoxy-D-glycerol-D-galacto-non-2-enoic acid) and 4-guanidino-Neu5Ac2en (5-acetylamino-2,6-anhydro-4-guanidino-3,4,5- trideoxy-D-glycerol-D-galacto-non-2-enoic acid), which s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c713f7e17598054976b9dcd1f7946c8
https://europepmc.org/articles/PMC163053/

Microsecond dynamics of H10N7 influenza neuraminidase reveals the plasticity of loop regions and drug resistance due to the R292K mutation.

Autor: Sk MF; Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore, India.; Theoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA., Samanta S; Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore, India., Poddar S; Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore, India., Kar P; Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore, India.

Publikováno v: Journal of computational chemistry [J Comput Chem] 2024 Feb 15; Vol. 45 (5), pp. 247-263. Date of Electronic Publication: 2023 Oct 03.

SCREENING OF POTENTIAL ANTI-INFLUENZA AGENTS FROM JUGLANS MANDSHURICA MAXIM. BY DOCKING AND MD SIMULATIONS.

Autor: YANG, Y.¹ yang-yu-chun@163.com, YANG, Z.² yzws-123@163.com, LIU, J.³, WU, F.², YUAN, X.⁴

Publikováno v: Digest Journal of Nanomaterials & Biostructures (DJNB). Jan-Mar2015, Vol. 10 Issue 1, p43-57. 15p. 6 Diagrams, 1 Chart, 2 Graphs.

Designing interactions by control of protein–ligand complex conformation: tuning arginine–arene interaction geometry for enhanced electrostatic protein–ligand interactions.

Autor: Noresson, A.-L., Aurelius, O., Öberg, C. T., Engström, O., Sundin, A. P., Håkansson, M., Stenström, O., Akke, M., Logan, D. T., Leffler, H., Nilsson, U. J.

Publikováno v: Chemical Science; 1/28/2018, Vol. 9 Issue 4, p1014-1021, 8p