Zobrazeno 1 - 10
of 22
pro vyhledávání: '"T J, Wickham"'
Publikováno v:
Gene Therapy. 8:938-945
Murine lymphocytes are relatively refractory to efficient transfection or retroviral gene transduction. Adenovirus has been used as a vector to transduce a wide variety of cell types. Several advantages of adenoviruses are their ability to transduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b38aeabc04079f69370d47998c8444
https://doi.org/10.1038/sj.gt.3301487
https://doi.org/10.1038/sj.gt.3301487
Autor:
T J, Wickham
Publikováno v:
Gene Therapy. 7:110-114
The use of targeted viral vectors to localize gene transfer to specific cell types holds many advantages over conventional, non-targeted vectors currently used in gene therapy. The resulting improvements in gene localization from targeted adenovirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c56cc6b421d2bc2d53c7caa0c2e350
https://doi.org/10.1038/sj.gt.3301115
https://doi.org/10.1038/sj.gt.3301115
Publikováno v:
Europe PubMed Central
We have analyzed the binding of adenovirus (Ad) serotypes from subgroups B, C, and D through fiber-virus and fiber-fiber cross-competition experiments. Since viruses in these distinct subgroups display markedly different tropisms, it was unexpected t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f7ebde83cee357e032b825e178aad7
https://doi.org/10.1128/jvi.70.11.7614-7621.1996
https://doi.org/10.1128/jvi.70.11.7614-7621.1996
Autor:
Alena Lizonova, Imre Kovesdi, D M Segal, Peter W. Roelvink, M. E. Carrion, Gai Mi Lee, T J Wickham
Publikováno v:
Journal of Virology. 70:6831-6838
A major hurdle to adenovirus (Ad)-mediated gene transfer is that the target issue lacks sufficient levels of receptors to mediate vector attachment via its fiber coat protein. Endothelial and smooth muscle cells are primary targets in gene therapy ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad098ff75095d10bdd63b7bdfd373dc6
https://doi.org/10.1128/jvi.70.10.6831-6838.1996
https://doi.org/10.1128/jvi.70.10.6831-6838.1996
Autor:
T. J. Wickham, Glen R. Nemerow
Publikováno v:
Biotechnology Progress. 9:25-30
A novel insect cell line from Trichoplusia ni, BTI-Tn 5B1-4 (Tn 5), was compared to Spodoptera frugiperda, Sf 9, cells for production of two recombinant secreted proteins: truncated Epstein-Barr viral attachment protein (EBV gp105) and truncated, sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acbf610d682692faca86ef0093716f6
https://doi.org/10.1021/bp00019a004
https://doi.org/10.1021/bp00019a004
Publikováno v:
Journal of General Virology. 73:3185-3194
The kinetic and equilibrium attachment of Autographa californica nuclear polyhedrosis virus (AcMNPV) to seven insect cell lines was evaluated. Kinetic experiments revealed differences of up to 10-fold in the infection rates among cell lines. Equilibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4a3e1afca4fba623ff077276c28194
https://doi.org/10.1099/0022-1317-73-12-3185
https://doi.org/10.1099/0022-1317-73-12-3185
Publikováno v:
Biotechnology Progress. 8:391-396
Eight cell lines derived from the insects Spodoptera frugiperda, Trichoplusia ni, Mamestra brassicae, and Estigmene acrea were evaluated for recombinant β-galac-tosidase and infectious virus production following infection with the baculovirus Autogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d1cf2a6855cd16933e8d0368dcb528
https://doi.org/10.1021/bp00017a003
https://doi.org/10.1021/bp00017a003
Publikováno v:
Biotechnology Letters. 13:483-488
Defective interfering particles, present within a high passage inoculum ofAutographa californica nuclear polyhedrosis virus (AcMNPV), interfered with recombinant β-galactosidase and infectious virus production in three insect cell lines. These parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48f28f39f5dbfc3109228a060116fbbc
https://doi.org/10.1007/bf01049204
https://doi.org/10.1007/bf01049204
Autor:
Bruno Quesnel, Rodolphe Vereecque, Ricardo Gonzalez, Aurore Saudemont, T J Wickham, Pierre Fenaux, Dominique Hetuin
Publikováno v:
Gene therapy. 10(3)
Top of pageAbstract The majority of immunotherapy-based gene therapy protocols consist of ex vivo gene transfer in tumor cells. To prevent further in vivo growth, modified cells must be irradiated before reinjection into patients. The present study e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12509064ccf9aa06ab48c5c498a1d44
https://pubmed.ncbi.nlm.nih.gov/12571630
https://pubmed.ncbi.nlm.nih.gov/12571630
Autor:
Robert R. Granados, Kevin A. McKenna, T. J. Wickham, Michael L. Shuler, H. A. Wood, Thomas R. Davis
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 29:388-390
A recombinant Autographa californica baculovirus expressing secreted alkaline phosphatase (SEAP) gene was used to evaluate the expression of a secreted glycoprotein in eight insect cell lines derived from Spodoptera frugiperda, Trichoplusia ni, Mames
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c82e7fd0495db9fd70c36c504f3c2da
https://doi.org/10.1007/bf02633986
https://doi.org/10.1007/bf02633986