Výsledky vyhledávání

Identification of a protein altered in mutants resistant to microtubule inhibitors as a member of the major heat shock protein (hsp70) family

Autor: S Ahmad, R Ahuja, T J Venner, R S Gupta

Publikováno v: Molecular and Cellular Biology. 10:5160-5165

A major cellular protein (P2; approximately 70 kilodaltons) which is altered in Chinese hamster ovary (CHO) cell mutants resistant to the microtubule inhibitors colchicine and podophyllotoxin has been shown to correspond to the constitutive form of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::607f9069062e9d55766d8412da8f9551
https://doi.org/10.1128/mcb.10.10.5160

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cis-Urocanic acid does not induce the expression of immunosuppressive cytokines in murine keratinocytes

Autor: M, Zak-Prelich, M, Norval, T J, Venner, Y, Bisset, C, Walker, T S, Rafferty, D N, Sauder, R C, McKenzie

Publikováno v: Photochemistry and photobiology. 73(3)

trans-Urocanic acid (UCA) acts as a chromophore for UV radiation in the epidermis and isomerizes to cis-UCA which then initiates some of the changes leading to UV-induced immunosuppression. The mechanism of the immunomodulation by cis-UCA is unknown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fce70f8cc3eef4c4a270becc890380be
https://pubmed.ncbi.nlm.nih.gov/11281019

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The effects of standard and low molecular weight heparin on bone nodule formation in vitro

Autor: M, Bhandari, J, Hirsh, J I, Weitz, E, Young, T J, Venner, S G, Shaughnessy

Publikováno v: Thrombosis and haemostasis. 80(3)

Previously, we demonstrated in a rat model of heparin-induced osteoporosis that low molecular weight heparin (LMWH) produces less bone loss than unfractionated heparin, and that only heparin increases osteoclast number and activity. In contrast, both

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::502e49fb015c3eb9ee0f2ed00061616e
https://pubmed.ncbi.nlm.nih.gov/9759620

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Augmentation of interleukin-6 (IL-6) expression in squamous carcinoma cells and normal human keratinocytes treated with recombinant anti-neoplastic protein (ACP)

Autor: R C, McKenzie, T J, Venner, D N, Sauder, H, Farkas-Himsley

Publikováno v: Anticancer research. 14(3A)

A protein purified from Eschericheri coli has previously been shown to have cytotoxic effects on neoplastic cells of several lineages both in vitro and in vivo. Accordingly, this protein has been named anti-neoplastic protein (ACP). Although ACP kill

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0046db19a6dddc653c19626e40dcc59b
https://pubmed.ncbi.nlm.nih.gov/8074468

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Effects of antimitotic and antimitochondrial agents on the cellular distribution of microtubules and mitochondria

Autor: A K, Dudani, R C, Austin, T J, Venner, R S, Gupta

Publikováno v: Cytobios. 63(253)

Using antibodies to a mitochondrial molecular chaperone class of protein, which is specifically altered in mutants resistant to microtubule (MT) inhibitors, the effect of a number of MT and mitochondrial inhibitors on the cellular distribution of mit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::306d0594b375bcd06a279cc99d4432a8
https://pubmed.ncbi.nlm.nih.gov/2276284

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