Zobrazeno 1 - 6
of 6
pro vyhledávání: '"T J, Velu"'
Publikováno v:
Molecular and Cellular Biology. 11:6026-6033
We have previously used a series of insertion-deletion mutants of the mutationally activated v-rasH gene to identify several regions of the encoded protein that are dispensable for cellular transformation (B. M. Willumsen, A. G. Papageorge, H.-F. Kun
Publikováno v:
The New biologist. 3(4)
A variety of cancer cells overexpress transforming growth factor alpha (TGF alpha), a mitogenic peptide. A cDNA sequence coding for the full-length human TGF alpha precursor protein was subcloned into a retroviral expression vector and introduced int
We have constructed an efficient new retroviral vector containing strong promoting elements derived from the Friend murine leukemia virus (F-MuLV) long terminal repeat (LTR) and have used the vector to demonstrate that overexpression of human c-fps/f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ad3ec5961ea38ffed5df0fd6e1e23b
https://europepmc.org/articles/PMC251218/
https://europepmc.org/articles/PMC251218/
The rat-derived Harvey murine sarcoma virus (Ha-MuSV) contains a transduced ras oncogene activated by two missense mutations and flanked by rat retroviruslike VL30 sequences. Ha-MuSV induces focal transformation of mouse NIH 3T3 cells in vitro and tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533317a01e27f28bc9284c1616f0a018
https://europepmc.org/articles/PMC247837/
https://europepmc.org/articles/PMC247837/
Publikováno v:
The New England journal of medicine. 318(15)
Publikováno v:
The Biochemical journal. 254(1)
NIH 3T3 cells, which express a small number of EGF (epidermal growth factor) receptors, are poorly responsive to EGF. However, when the same cells overexpress the cloned human EGF receptor (EGFR T17 cells), they display EGF-dependent transformation.