Zobrazeno 1 - 10
of 53
pro vyhledávání: '"T J, Scallen"'
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 12, Pp 2241-2253 (1994)
The role of oxysterols as regulatory molecules in the suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity was investigated in the intact rat in response to an acute dietary cholesterol challenge. When rats were fed highl
Externí odkaz:
https://doaj.org/article/d79674f78b88439c934e1bcdc7465e94
Autor:
E Hansbury, T J Scallen
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 7, Pp 921-929 (1980)
A three-step procedure has been developed for the separation of complex mixtures of sterol intermediates in cholesterol biosynthesis. The method has been applied to the separation of sterol intermediates formed from [14C]mevalonate by normal rat hepa
Externí odkaz:
https://doaj.org/article/aaa944de61d944baa33e8b636fe9bc06
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 4, Pp 645-652 (1982)
Simple methods for determining the enantiomeric purity of mevalonolactone and linalool by NMR using the chiral shift reagent Eu(hfc)3 are reported. These methods are more reliable than polarimetry and require only a few milligrams of sample to detect
Externí odkaz:
https://doaj.org/article/0b72975f46f347e8b92fcd999dfa3e22
Publikováno v:
Journal of Lipid Research, Vol 18, Iss 3, Pp 408-413 (1977)
Two assays for the quantitative measurement of HMG-CoA reductase, the major regulatory enzyme in hepatic cholesterol biosynthesis, are described. The first of these procedures employs thin-layer chromatography (TLC) of the reaction product on plastic
Externí odkaz:
https://doaj.org/article/6d8456bbd89a4629b1dbc985758f564f
Autor:
E Hansbury, T J Scallen
Publikováno v:
Journal of Lipid Research, Vol 19, Iss 6, Pp 742-746 (1978)
A highly efficient technique has been developed for the resolution of several sterols that are intermediates in the biosynthesis of cholesterol and that differ only by one carbon-carbon double bond or by one methyl group. The technique described util
Externí odkaz:
https://doaj.org/article/c4357f7596fb4aefadf1af4ff212c63f
Autor:
Peter G. Pentchev, Roscoe O. Brady, A Pastuszyn, J T Billheimer, Jerome F. Strauss, M T Vanier, T J Scallen, Calvin F. Roff
Publikováno v:
Journal of Biological Chemistry. 267:15902-15908
Hepatic sterol carrier protein-2 (SCP2) and sterol carrier protein-X (SCPx) levels in normal and in mutant Niemann-Pick Type C mice were determined by immunoblotting with antiserum against rat SCP2. A 14-kDa protein (SCP2) was detected in the cytosol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dfa2593168dd34f2f8a47a1150bb519
https://doi.org/10.1016/s0021-9258(19)49619-1
https://doi.org/10.1016/s0021-9258(19)49619-1
Publikováno v:
Journal of Biological Chemistry. 266:10602-10607
The effect of sterol carrier protein-2 (SCP-2) on dolichol biosynthesis by rat liver microsomes was investigated. cis-Prenyltransferase activity was stimulated 7-fold in the presence of 5 micrograms of purified SCP-2/mg of microsomal protein, which w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3147c1fbe843267b29281d55934a5905
https://doi.org/10.1016/s0021-9258(18)99266-5
https://doi.org/10.1016/s0021-9258(18)99266-5
Publikováno v:
Journal of Biological Chemistry. 266:5486-5496
The potential role of liver fatty acid binding protein (L-FABP) in modulating cellular sterol distribution was examined in mouse L-cell fibroblasts transfected with cDNA encoding L-FABP. L-cells were chosen because they contain only a small amount of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5760881ab8afed096df2884d4e76c95c
https://doi.org/10.1016/s0021-9258(19)67621-0
https://doi.org/10.1016/s0021-9258(19)67621-0
Publikováno v:
Journal of lipid research. 36(12)
Cholesterol enrichment of vascular smooth muscle cells, as occurs under conditions of hypercholesterolemia and atherosclerosis, is accompanied by specific changes in cholesterol metabolism and in intracellular cholesterol trafficking. Sterol-carrier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27ef3bfa29d13345476662b7adb9eba1
https://pubmed.ncbi.nlm.nih.gov/8847489
https://pubmed.ncbi.nlm.nih.gov/8847489
Publikováno v:
Cancer research. 54(21)
Novel compounds based upon the thiol N-(carboxy)-beta-alanyl-cysteamine (vitaletheine) have strikingly potent and seemingly diverse biological activities. Concentrations of vitaletheine modulators from 1 femtograms/ml to 100 picograms/ml medium regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a8df9da1a1ea827847417f39fcbd721
https://pubmed.ncbi.nlm.nih.gov/7923208
https://pubmed.ncbi.nlm.nih.gov/7923208