Zobrazeno 1 - 10
of 17
pro vyhledávání: '"T J, Maher"'
Publikováno v:
Journal of Autonomic Pharmacology. 18:281-286
1 The involvement of nitric oxide (NO) in the non-adrenergic non-cholinergic inhibitory (NANC-i) neurotransmission was evaluated in guinea-pigs anaesthetized with chloralose–urethane, using a tracheal pouch preparation. 2 The tracheal pouch, a surg
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(3)
A fundamental feature of any drug designed to treat a disease of the central nervous system is the ability to cross the blood-brain barrier. Passage across the blood-brain barrier of AIT-082, a cognitive enhancer, was investigated in mice. [(14)C]AIT
Publikováno v:
Brain research. 865(2)
Steroid sulfatase inhibitors can enhance the concentration of the neurosteroid DHEAS in rat brain. Previous studies have demonstrated that the steroid sulfatase inhibitor (p-O-sulfamoyl)-N-tetradecanoyl tyramine (DU-14) could reverse scopolamine indu
Autor:
T J, Maher
Publikováno v:
Progress in brain research. 122
While many of the above examples support a role of these dietary components in modifying the synthesis, storage, release and actions of various neurotransmitter molecules in the central nervous system, most of the responses to eating everyday foods a
Autor:
T J Maher, Paul J. Wellman
Publikováno v:
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 23(7)
'Fen-phen' refers to the off-label combination of the appetite suppressants fenfluramine and phentermine. The rationale for the fen-phen combination was that the two drugs exerted independent actions on brain satiety mechanisms so that it was possibl
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 6(2)
Monocytoid B-cell lymphoma (MBCL) is a low-grade neoplasm considered to be the neoplastic counterpart to monocytoid B-lymphocytes, derived from marginal zone lymphocytes. Recently, a 72-yr-old woman presented with urinary symptoms of burning, urgency
Publikováno v:
Life sciences. 52(15)
While oral administration of therapeutic doses of phenylpropanolamine (PPA) does little to cardiovascular function in humans, intravenous doses administered to experimental animals are known to alter heart rate and blood pressure. Previous in vivo an
Publikováno v:
ChemInform. 21
Autor:
K M, Hull, T J, Maher
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 255(2)
The effects of L-tyrosine (L-TYR) on the anorectic activity of several mixed-acting sympathomimetics were determined during the dark cycle in rats made hyperphagic by food deprivation. L-TYR (200 mg/kg) significantly potentiated the anorectic activit
Autor:
Richard J. Wurtman, T. J. Maher
Publikováno v:
Journal of Neural Transmission. 70:169-173
All aspartame does given to humans cause greater elevations in plasma (and, presumably, brain) phenylalanine than in plasma tyrosine. In contrast, doses of aspartame usually used in experiments on rodents preferentially elevate tyrosine. Since phenyl