Zobrazeno 1 - 10
of 26
pro vyhledávání: '"T J, Helmerhorst"'
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 145(14)
Since the 1940s, diethylstilbestrol (DES) has been administered to about three million pregnant women in the United States and in the Netherlands, between 1947 and 1975, to about 220,000. The most important consequences described are: for DES mothers
Autor:
T J, Helmerhorst
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 144(39)
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 144(35)
More than 99% of all cervical cancers contain high risk HPV. Only a persistent infection with high risk HPV of the cervical epithelium results in cervical cancer. Because the risk of cervical cancer is identical for all different HPV types, tests whi
Autor:
A E, Weel, A G, Uitterlinden, I C, Westendorp, H, Burger, S C, Schuit, A, Hofman, T J, Helmerhorst, J P, van Leeuwen, H A, Pols
Publikováno v:
The Journal of clinical endocrinology and metabolism. 84(9)
Age at menopause and risk of hysterectomy have strong genetic components, but the genes involved remain ill defined. We investigated whether genetic variation at the estrogen receptor (ER) gene contributes to the variability in the onset of menopause
Autor:
H J, Bontkes, M, van Duin, T D, de Gruijl, M F, Duggan-Keen, J M, Walboomers, M J, Stukart, R H, Verheijen, T J, Helmerhorst, C J, Meijer, R J, Scheper, F R, Stevens, P A, Dyer, P, Sinnott, P L, Stern
Publikováno v:
International journal of cancer. 78(2)
High-risk human papillomavirus (HPV) infection plays an important role in cervical intra-epithelial neoplasia (CIN), but HPV infection alone is not sufficient for progression to cervical cancer. Several lines of evidence suggest that cellular immune
Autor:
C J, Meijer, T J, Helmerhorst, L, Rozendaal, J C, van der Linden, F J, Voorhorst, J M, Walboomers
Publikováno v:
Histopathology. 33(1)
Autor:
T D, de Gruijl, H J, Bontkes, J M, Walboomers, M J, Stukart, F S, Doekhie, A J, Remmink, T J, Helmerhorst, R H, Verheijen, M F, Duggan-Keen, P L, Stern, C J, Meijer, R J, Scheper
Publikováno v:
Cancer research. 58(8)
T-cell-mediated immune responses against oncogenic human papillomaviruses (HPVs) are believed to play a role in the prevention of cervical carcinogenesis. The in vitro production of interleukin 2 by CD4+ T helper (Th) cells in response to overlapping
Publikováno v:
Anticancer research. 17(6D)
Glutathione S-transferase pi (GST pi) is involved in a variety of cell detoxification processes. In the uterine cervix its presence has been associated with high grade cervical intraepithelial neoplasia (CIN), but the reports are conflicting. For thi
Publikováno v:
International journal of cancer. 73(2)
Distribution of the photosensitizer Foscan (meta-tetrahydroxyphenylchlorin, mTHPC), after i.v. or i.p. injection, was investigated in Wag/Rij rats bearing i.p. tumours. These results were compared with the efficacy of mTHPC-mediated photodynamic ther
Autor:
R C, Rietbroek, M S, Schilthuis, P J, Bakker, J D, van Dijk, A J, Postma, D, González González, A J, Bakker, J, van der Velden, T J, Helmerhorst, C H, Veenhof
Publikováno v:
Cancer. 79(5)
The biologic rationale for combining cisplatin with locoregional hyperthermia (HT) relates to the potentiating effect of HT on cisplatin cytotoxicity.Patients with recurrent cervical carcinoma, who had a pelvic recurrence after radiotherapy, were tre