Zobrazeno 1 - 10
of 11
pro vyhledávání: '"T J, Bach"'
Autor:
Catherine D. Strader, M J Forrest, Jennifer E. Hutchins, R R Miller, Shuet Hing L Chiu, D. E. Macintyre, G J Hom, R A Stearns, T J Bach, Margaret A. Cascieri, Linda J. Kelly, A M Amend, Joseph M. Metzger, D Carroll, Mari R. Candelore, Xiao-Ming Guan, B Hegarty-Friscino, E R Parmee, Edward J. Brady, Liping Deng, Robert J. Mathvink, Richard Saperstein, M. H. Fisher, J M Barker, H O Ok
Publikováno v:
Journal of Clinical Investigation. 101:2387-2393
Activation of beta3 adrenergic receptors on the surface of adipocytes leads to increases in intracellular cAMP and stimulation of lipolysis. In brown adipose tissue, this serves to up-regulate and activate the mitochondrial uncoupling protein 1, whic
Autor:
G J, Hom, M J, Forrest, T J, Bach, E, Brady, M R, Candelore, M A, Cascieri, D J, Fletcher, M H, Fisher, S A, Iliff, R, Mathvink, J, Metzger, V, Pecore, R, Saperstein, T, Shih, A E, Weber, M, Wyvratt, P, Zafian, D E, MacIntyre
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 297(1)
The effects of two beta(3)-adrenergic receptor agonists, (R)-4-[4-(3-cyclopentylpropyl)-4,5-dihydro-5-oxo-1H-tetrazol-1-yl]-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]benzenesulfonamide and (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)- et
Publikováno v:
Biochemical Society transactions. 28(6)
Plant isoprenoids represent a large group of compounds with a wide range of physiological functions. In the cytosol, isoprenoids are synthesized via the classical acetate/mevalonate pathway. In this pathway, farnesyl diphosphate (FPP) occupies a cent
Publikováno v:
The Plant journal : for cell and molecular biology. 22(5)
3-Hydroxy-3-methylglutaryl-coenzyme A synthase (HMGS) is an enzyme in mevalonate biosynthesis. In plants, investigations have focused on HMG CoA reductase (HMGR) and less is known of the preceding enzyme, HMGS. To understand the regulation of HMGS, w
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(1)
The role of inducible nitric oxide synthase (iNOS) was examined in the hypotension and vascular hyporesponsiveness to norepinephrine (NE) invoked by lipopolysaccharide (LPS) in pentobarbital-anesthetized rats. Saline, dexamethasone (DEX), NG-monometh
Autor:
S B, Hwang, M H, Lam, D M, Szalkowski, D E, MacIntyre, T J, Bach, S, Luell, R, Meuer, S P, Sahoo, A W, Alberts, J C, Chabala
Publikováno v:
Journal of lipid mediators. 7(2)
MK 287 (L-680,573), a tetrahydrofuran analog, potently inhibited [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1 +/- 1.5, 3.2 +/- 0.7, and 5.49 +/- 2.3 nM, respectively. The inhibitory
Autor:
T. J. Bach
Publikováno v:
Journal of the American Oil Chemists' Society. 65:591-595
Autor:
T. J. Bach, W. D. Nes
Publikováno v:
Proceedings of the Royal Society of London. Series B. Biological Sciences. 225:425-444
Primary leaf tissue from light and dark grown wheat seedlings incubated with [2-14C]acetate and [2-3H]mevalonolactone (MVA) synthesized doubly labelled sterols and long chain fatty alcohols (LCFA). While [2-3H]MVA was incorporated into LCFA as effici
Autor:
T J, Bach, H K, Lichtenthaler
Publikováno v:
Zeitschrift fur Naturforschung. Section C, Biosciences. 38(3-4)
1) In kinetic studies, mevinolin proved to be a highly specific inhibitor of partially purified yeast HMG-CoA reductase (Ki = 3.5 nM towards HMG-CoA) and of microsomal HMG-CoA reductase from etiolated radish seedlings (Ki = 2.2 nM). At low concentrat
Autor:
T. J. Bach, Hartmut K. Lichtenthaler
Publikováno v:
Naturwissenschaften. 69:242-243