Zobrazeno 1 - 10
of 15
pro vyhledávání: '"T Iu, Dubskaia"'
Autor:
V Iu, Usov, M L, Balianin, A I, Bezlepkin, A A, Churin, T Iu, Dubskaia, T L, Vetoshkina, V D, Filimonov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 76(10)
Preclinical evaluation of a 0.5 M solution of the manganese(II)- trans-1,2-diaminocyclohexane-N,N,N',N'-tetraacetate complex (Mn-DCTA, Cyclomang) has been carried out with a view to substitution of potentially toxic gadolinium-containing paramagnetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d74ca6bb26fb091044004c997deace1c
https://pubmed.ncbi.nlm.nih.gov/24400387
https://pubmed.ncbi.nlm.nih.gov/24400387
Publikováno v:
Vestnik Rossiiskoi akademii meditsinskikh nauk. (11)
The influence of various antineoplastic preparations (farmorubicin, paclitaxel, etoposide, platidiam) on morphological and functional status of the liver in experimental animals was studied. It is shown, that all these antineoplastic drugs possess st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b6e9d5e8892f304bc45d59c192b6790
https://pubmed.ncbi.nlm.nih.gov/20017402
https://pubmed.ncbi.nlm.nih.gov/20017402
Autor:
A A, Churin, G V, Karpova, T I, Fomina, T V, Vetoshkina, T Iu, Dubskaia, O L, Voronova, V D, Filimonov, M L, Belianin, V Iu, Usov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 71(4)
We have carried out a preclinical toxicological investigation (acute toxicity evaluation) of Mangascan (0.5 M solution of manganese(II) - EDTA complex) and Pentamang (0.5 M solution of manganese(II) - DTPA complex), a new paramagnetic contrast agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fed3abfc7f16b46daf2472279a3d9297
https://pubmed.ncbi.nlm.nih.gov/18819441
https://pubmed.ncbi.nlm.nih.gov/18819441
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 69(1)
Irinotecan (campto) and etoposide cause the loss cells due to apoptosis, the early development of hypoplasia in bone marrow and lymphoid organs, and pancytopenia in peripheral blood upon single intravenous injection in maximum tolerated doses to whit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d250a1772c9c480b71b1aeabc5ab6f7e
https://pubmed.ncbi.nlm.nih.gov/16579059
https://pubmed.ncbi.nlm.nih.gov/16579059
Autor:
G V, Karpova, T I, Fomina, T V, Vetoshkina, T G, Borovskaia, O L, Voronova, T Iu, Dubskaia, N I, Suslov, E V, Abramova, O P, Loskutova, E Iu, Sherstoboev, V G, Pashinskiĭ, T N, Povet'eva, A A, Semenov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 65(3)
The safety of bayacon, a new drug based on Baikal aconite intended for the treatment of inflammation-proliferative dermatitis (psoriasis), was studied on a preclinical level. With respect to a single introduction in rats and mice, the drug is classif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a96106024f61ae3f0a618d56c2d5167
https://pubmed.ncbi.nlm.nih.gov/12227102
https://pubmed.ncbi.nlm.nih.gov/12227102
Autor:
G V, Karpova, T I, Fomina, T V, Vetoshkina, T G, Borovskaia, O L, Voronova, T Iu, Dubskaia, V V, Udut, M Iu, Khlusova
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 64(1)
A new D-glucuronic acid (DGA) preparation was studied for toxicological safety on a preclinical level. The results obtained upon a single acute DGA administration in rats, mice, and rabbis showed that the drug exhibits moderate toxicity. A one-month
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::039e3fdef758d9c8d02454524979e9a0
https://pubmed.ncbi.nlm.nih.gov/11544811
https://pubmed.ncbi.nlm.nih.gov/11544811
Autor:
G V, Karpova, T I, Fomina, T V, Vetoshkina, T G, Borovskaia, O L, Voronova, T Iu, Dubskaia, M E, Poluéktova, E A, Timina, E S, Smol'ianinov, V F, Turetskova
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 63(4)
A new drug preparation ecorsin based on the dry aspen bark extract was studied for toxicological safety on a preclinical stage. The drug exhibited no toxicity upon a single administration to rats and mice (both male and female). The intragastric admi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::acd5d92b792e7ff0bd6bcb31a5e39be9
https://pubmed.ncbi.nlm.nih.gov/11022311
https://pubmed.ncbi.nlm.nih.gov/11022311
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 62(1)
A single intravenous infusion of 4.5 mg/kg of the new antineoplastic drug platidium induces structural-metabolic changes in the liver of rats (necrosis of hepatocytes, decrease of the glycogen and RNA content and accumulation of lipids in the cytopla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f24f5d3b5872f6a269fc9161c591e591
https://pubmed.ncbi.nlm.nih.gov/10198772
https://pubmed.ncbi.nlm.nih.gov/10198772
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 126(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8a9b507fa6680520d03898e816be02b
https://pubmed.ncbi.nlm.nih.gov/9883369
https://pubmed.ncbi.nlm.nih.gov/9883369
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 61(1)
It was shown in experiments on rats that intravenous infusion of the antitumor drug vepesid in a maximum tolerated dose causes stimulation of free-radical oxidation and changes in the fractional composition of lipids and phospholipids in the hepatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::301d21e5e6706835bd2924dcb8b26796
https://pubmed.ncbi.nlm.nih.gov/9575414
https://pubmed.ncbi.nlm.nih.gov/9575414