Zobrazeno 1 - 10
of 69
pro vyhledávání: '"T I Torkhovskaia"'
Autor:
N V Medvedeva, E G Tikhonova, V N Prozorovskiĭ, A V Shironin, T S Zakharova, T I Torkhovskaia, O. M. Ipatova, M A Sanzhakov
Publikováno v:
Biomeditsinskaya Khimiya. 57:671-676
The ultrafine formulation on the base of plant phosphatidylcholine and antiinflammatory remedy indomethacin with nanoparticles less than 50 nm was obtained. Drug bioavailability after its peroral administration to rats was more than 2 fold higher as
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 1:1-8
The review highlights the membrane aspect of cholesterol efflux from cell membranes to high density lipoproteins (HDL), an initial stage of reverse cholesterol transport to liver. In addition to traditional viewpoints considering cholesterol transpor
Autor:
M A, Sanzhakov, O M, Ipatova, T I, Torkhovskaia, V N, Prozorovskiĭ, E G, Tikhonova, O S, Druzhilovskaia, N V, Medvedeva
Publikováno v:
Vestnik Rossiiskoi akademii meditsinskikh nauk. (8)
The increase of tuberculosis incidence in last decade stimulated elaboration of both new antituberculous drugs and also searches ofoptimiting delivery systems for existing drugs. It is determined by their side effects and low bioavailability of effec
Autor:
A V, Shironin, O M, Ipatova, N V, Medvedeva, V N, Prozorovskiĭ, E G, Tikhonova, T S, Zakharova, M A, Sanzhakov, T I, Torkhovskaia
Publikováno v:
Biomeditsinskaia khimiia. 57(6)
The ultrafine formulation on the base of plant phosphatidylcholine and antiinflammatory remedy indomethacin with nanoparticles less than 50 nm was obtained. Drug bioavailability after its peroral administration to rats was more than 2 fold higher as
Autor:
T I Torkhovskaia, V. S. Baranova, Alexander I. Archakov, N. D. Ivanova, A V Shironin, N V Medvedeva, V N Prozorovskiĭ, O. M. Ipatova
Publikováno v:
Biomeditsinskaia khimiia. 56(1)
The recent studies in nanotechnology resulted in the development of novel formulations with improved bioavailability. This is especially important for oral administered drugs as the most convenient formulations. The current review deals with the proc
Publikováno v:
Vestnik Rossiiskoi akademii meditsinskikh nauk. (5)
The extensive development of nanotechnologies in the last two decades has brought about new understanding of plasma lipoproteins (LP) as natural drug nanocarriers that escape interaction with immune and reticuloendothelial systems. Drugs bound to LP
Autor:
O S, Strekalova, V F, Uchaĭkin, O M, Ipatova, T I, Torkhovskaia, N V, Medvedeva, G I, Storozhakov, A I, Archakov
Publikováno v:
Biomeditsinskaia khimiia. 55(4)
The review presents the modern concepts on biochemical mechanisms of processes, that result in comatose states (CS), with emphasis on the search of new therapeutic approaches. CS of various origin causes severe suppression of brain cells functioning
Publikováno v:
Biomeditsinskaia khimiia. 55(2)
The complexes of phospholipids nanoparticles (as the injection form of newly developed hepatoprotector phosphogliv) with the antitumor drug doxorubicin or with glucocorticoid budesonide have been investigated for their pharmacological activity in com
Publikováno v:
Biomeditsinskaia khimiia. 53(4)
The efficiency of methotrexate use in basic therapy of rheumatoid arthritis is limited because of risk of side effects and fast drug efflux from zone of joints as well. The new stabilized form of methotrexate was elaborated with phospholipid micelles
Publikováno v:
Biomeditsinskaia khimiia. 52(2)
The review highlights the membrane aspect of cholesterol efflux from cell membranes to high density lipoproteins (HDL), an initial stage of reverse cholesterol transport to liver. Special attention is paid to ABC-A1 transporter and membrane SR-B1 rec