Zobrazeno 1 - 10
of 14
pro vyhledávání: '"T I Michalak"'
Autor:
L Al-Yasiri, R P Davis, S D'souza, T R Patel, F van der Meer, D P Whiteside, T I Michalak, C N Jenne, C S Coffin
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 6:69-70
Background Hepatitis B virus (HBV) infections are one of the largest global infectious disease burdens, despite the availability of a preventative vaccine. The virus infects the liver which is a vital organ that plays a critical role in homeostasis d
Autor:
Krystyna Mazan-Mamczarz, Kevin G. Becker, James J. Steinhardt, Parameswary A. Muniandy, T I Michalak, Ferenc Livak, Yonqing Zhang, C P Corkum, Qing-Rong Chen, Raymond J. Peroutka, Ronald B. Gartenhaus, Simone Houng, Elin Lehrmann, Annie Y. Chen, Ari L. Landon, Bojie Dai, M. Shlyak, R. Talwani
Publikováno v:
Oncogene
B-cell receptor (BCR) signaling is essential for the development of B cells and has a critical role in B-cell neoplasia. Increasing evidence indicates an association between chronic hepatitis C virus (HCV) infection and B-cell lymphoma, however, the
Autor:
P B, Sugden, T N Q, Pham, S, Ratnarajah, B, Cameron, R, Bull, P A, White, T I, Michalak, A R, Lloyd, Lisa, Maher
Publikováno v:
Journal of viral hepatitis. 20(10)
Summary Occult hepatitis C virus (HCV) is a phenomenon where serum HCV RNA is not detected by sensitive commercial assays, but viral RNA is detected by ultrasensitive techniques. Occult HCV infection has not previously been studied in highly exposed,
Publikováno v:
Journal of viral hepatitis. 19(2)
Hepatitis C virus (HCV) and hepatitis B virus (HBV) frequently coinfect and persist long after clinical resolution. We assessed the incidence of low-level (occult) HCV infection (OCI) after sustained virological response (SVR) to standard anti-HCV th
Autor:
C S, Coffin, P M, Mulrooney-Cousins, M G, Peters, G, van Marle, J P, Roberts, T I, Michalak, N A, Terrault
Publikováno v:
Journal of viral hepatitis. 18(6)
The hepatitis B virus (HBV) replicates via an error-prone reverse transcriptase generating potential drug-resistant quasispecies. The degree of HBV variability in liver vs peripheral blood mononuclear cells (PBMC) in patients on long-term suppressive
SUMMARYThe Fas ligand (FasL)/Fas and the perforin-granzyme cytotoxic pathways presumably play a central role in the development of hepatocellular injury in viral hepatitis. To recognize the potential contribution of FasL and perforin-based cell killi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b920e47b40dc89c77c6eee88b28dcda
https://europepmc.org/articles/PMC1905398/
https://europepmc.org/articles/PMC1905398/
Autor:
T. I. Michalak, Joseph Lau, GraemeJ.M. Alexander, Roger Williams, A. L. W. F. Eddleston, B.M. McFarlane
Publikováno v:
Scopus-Elsevier
SUMMARY The susceptibility of hepatocytes from patients with chronic hepatitis B to complement-dependent cytotoxicity mediated by heterologous antibodies to hepatitis B virus core (anti-HBc) and surface (anti-HBc) antigens and to hepatic asialoglycop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe770fd665c8e9f395822eb2f191575
https://europepmc.org/articles/PMC1534334/
https://europepmc.org/articles/PMC1534334/
Publikováno v:
Tissue antigens. 45(5)
Two class I major histocompatibility complex (MHC) proteins with molecular masses of 43- and 39-kDa were identified in the cell surface membranes of normal woodchucks using a newly developed anti-woodchuck class I monoclonal antibody (mAb) B1b.B9 and
Publikováno v:
Clinical and experimental immunology. 98(1)
SUMMARY We have previously shown that mice challenged with the rat thyroglobulin (Tg) peptide TgP1 (corresponding to aa 2495–2511 of human Tg) develop experimental autoimmune thyroiditis (EAT) and produce IgG antibodies that cross-react with Tg fro
Autor:
T I, Michalak, B, Lin
Publikováno v:
Hepatology (Baltimore, Md.). 20(2)
Hepadnaviral antigens exposed on hepatocytes serve as targets and as possible modulators of immunopathogenic reactions causing liver damage. To identify molecular species of viral proteins at the liver cell surface and the relationship between their