Výsledky vyhledávání - "T I, Olkhovik"

Study of the Janus kinase 2 (JAK2) gene haplotype 46/1 association with driver mutations of chronic Ph-negative myeloproliferative neoplasms

Autor: I. А. Olkhovskiy, M. A. Stolyar, Yu. Yu. Komarovskiy, A. S. Gorbenko, V. I. Korchagin, E. A. Dunaeva, K. O. Mironov, V. I. Bakhtina, T. I. Olkhovik, E. V. Vasiliev, M. A. Mikhalev

Publikováno v: Russian journal of hematology and transfusiology. 67:377-387

Introduction. Haplotype JAK2 46/1 is associated with more frequent development of Ph-negative myeloproliferative neoplasms (MPN) and with an increased detection rate of the JAK2 V617F mutation. At the same time, the molecular mechanisms of such assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f77c73190051f30e010f0b9a114adb70
https://doi.org/10.35754/0234-5730-2022-67-3-377-387

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Use of the «BCR/ABL – multitest» kit in the algorithm of laboratory diagnostics of oncohematological diseases: economic aspects

Autor: M. A. Mikhalev, T I Olkhovik, M.A. Stolyar, E E Mochalova, K E Orlova, V I Bakhtina, E. V. Vasiliev, A. S. Gorbenko, I. A. Olkhovskiy

Publikováno v: Russian Clinical Laboratory Diagnostics. 66:571-576

Abnormal mRNAs of the hybrid BCR-ABL gene in the majority of cases initiate the synthesis of proteins with a mass of 210 kDa (p210), 190 kDa (p190), and 230 kDa (p230). Expression of the p210 variant is most common in CML (95% of cases), while the p1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31fe46c67a3bf4fe8e4d01241ef4598
https://doi.org/10.51620/0869-2084-2021-66-9-571-576

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Study of mRNA of WT1, BAALC, EVI1, PRAME and HMGA2 genes in whole blood samples

Autor: I. A. Olkhovskiy, A. S. Gorbenko, M. A. Stolyar, V. I. Bakhtina, M. A. Mikhalev, T. I. Olkhovik, A. B. Sudarikov, Yu. S. Sidorova, T. I. Pospelova, M. A. Kolesnikova, T. S. Kaporskaya, V. A. Lyskova

Publikováno v: Klinicheskaia laboratornaia diagnostika. 67(10)

Simultaneous quantitative measurement of mRNA of the WT1, BAALC, EVI1, PRAME and HMGA2 genes in whole blood samples reflects the specific pathological proliferative activity in acute leukemia and their ratio is promising as a diagnostic marker. The t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35592bbed34e51bc200e4c2624dd27ec
https://pubmed.ncbi.nlm.nih.gov/36315178

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Development of a method for the determination of the JAK2 gene mRNA in venous blood and assessment of its diagnostic value in oncohematology

Autor: M A, Stolyar, A S, Gorbenko, I A, Olkhovskiy, V I, Bakhtina, M A, Mikhalev, T I, Olkhovik, Yu Yu, Komarovskiy

Publikováno v: Klinicheskaia laboratornaia diagnostika. 66(6)

Overactive JAK pathway signaling is a hallmark of immune diseases and critically affects on inflammation and coagulation. A number of mutations in the JAK2 gene act as driving forces of myeloproliferative neoplasms (MPN), the pathogenesis of certain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ee116d7a4f00a270c6fd5d81fa7667f
https://pubmed.ncbi.nlm.nih.gov/34105916

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Development of a method for determining of the mRNA ROR1 in blood leukocytes

Autor: M.A. Stolyar, E.V. Martynova, M. G. Smelyanskaya, V I Bakhtina, M. A. Mikhalev, I. A. Olkhovskiy, T I Olkhovik, V.I. Moskov, A. S. Gorbenko, A. S. Hazieva

Publikováno v: Laboratornaya sluzhba. 10:32

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bee567c49cc584faaa55ad6cfd13875c
https://doi.org/10.17116/labs20211001132

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