Zobrazeno 1 - 10
of 12
pro vyhledávání: '"T I, Nicas"'
Publikováno v:
European Journal of Medicinal Chemistry. 32:459-478
Summary Resistance to the glycopeptide antibiotics vancomycin (V) and teicoplanin (T) in multi-resistant Gram-positive pathogens, particularly enterococci, is becoming a dramatic nosocomial problem. Besides the current lack of efficacious alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14a8b60333e44cba86f8dedfa8bb6e33
https://doi.org/10.1016/s0223-5234(97)84010-x
https://doi.org/10.1016/s0223-5234(97)84010-x
Publikováno v:
Journal of Antimicrobial Chemotherapy. 31:711-723
In-vitro synergy between vancomycin and ciprofloxacin against 44 enterococcal isolates was studied. Synergy occurred in chequerboard MIC determinations with six Enterococcus faecium strains resistant to both vancomycin and ciprofloxacin. The combinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d8831a0220b1ccca323a39f2bdec0c
https://doi.org/10.1093/jac/31.5.711
https://doi.org/10.1093/jac/31.5.711
Publikováno v:
ChemInform. 28
Summary Resistance to the glycopeptide antibiotics vancomycin (V) and teicoplanin (T) in multi-resistant Gram-positive pathogens, particularly enterococci, is becoming a dramatic nosocomial problem. Besides the current lack of efficacious alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::983cbd25ca3fbae7949b6a42b15d7cec
https://doi.org/10.1002/chin.199743302
https://doi.org/10.1002/chin.199743302
Publikováno v:
Medicinal research reviews. 17(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe4c3c7ee302ec11ff67f1cd29e72197
https://pubmed.ncbi.nlm.nih.gov/8979249
https://pubmed.ncbi.nlm.nih.gov/8979249
Autor:
A A Minnick, Marc C. Lavoie, A Brochu, T I Nicas, E K Dolence, M J Miller, J A McKee, F Malouin, N Brochu, T R Parr
Publikováno v:
Antimicrobial agents and chemotherapy. 36(10)
We describe here the mechanism of inhibition of two new siderophore-beta-lactam conjugates against Escherichia coli X580. One conjugate is a spermidine-based catechol siderophore-carbacephalosporin (JAM-2-263), and the other is an N5-acetyl-N5-hydrox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48a41dadc29c209a5342bb3ae42a26e
https://pubmed.ncbi.nlm.nih.gov/1444296
https://pubmed.ncbi.nlm.nih.gov/1444296
Publikováno v:
Antimicrobial Agents and Chemotherapy. 33:1477-1481
Gram-positive bacteria resistant to vancomycin are rare; but they include members of the genera Leuconostoc, Lactobacillus, and Pediococcus, as well as recently emerging vancomycin-resistant strains of Enterococcus faecium and Enterococcus faecalis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cead88f390791891a46b22071f4946
https://doi.org/10.1128/aac.33.9.1477
https://doi.org/10.1128/aac.33.9.1477
Autor:
T I, Nicas, B H, Iglewski
Publikováno v:
Antibiotics and chemotherapy. 36
Exoenzyme S is an extracellular ADPR transferase produced by P. aeruginosa. Forms of this enzyme that have thus far been purified are not toxic, however, exoenzyme S clearly contributes to the virulence of strain 388. Thus, a Tn1 mutant deficient in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::021e4ece627be2da4f7f2185e175ff4a
https://pubmed.ncbi.nlm.nih.gov/2988426
https://pubmed.ncbi.nlm.nih.gov/2988426
Autor:
T I, Nicas, B H, Iglewski
Publikováno v:
Advances in experimental medicine and biology. 185
Pseudomonas aeruginosa produces a large number of extracellular products which may play a role in pathogenesis. We have used genetic techniques to elucidate the relative contribution of these proteins to virulence, and as a method of producing safe t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::881023ba626395cd1a41e50d637c09e9
https://pubmed.ncbi.nlm.nih.gov/3000148
https://pubmed.ncbi.nlm.nih.gov/3000148
Autor:
R E Hancock, T I Nicas
Publikováno v:
Journal of bacteriology. 143(2)
It is well established that Pseudomonas aeruginosa cells grown in Mg2+-deficient medium acquire nonmutational resistance to the chelator ethylenediaminetetraacetate and to the cationic antibiotic polymyxin B; this type of resistance can be reversed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168443249791c437ea403bbb78184352
https://pubmed.ncbi.nlm.nih.gov/6259125
https://pubmed.ncbi.nlm.nih.gov/6259125
Autor:
L. E. Bryan, T. I. Nicas
In this study estimations of in vivo and in vitro gentamicin susceptibility for a series of strains of Pseudomonas aeruginosa were compared. The series included an extremely susceptible strain, typically susceptible strains by current susceptibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48da9d60858b471b5ac9fbac1b573c5b
https://europepmc.org/articles/PMC352333/
https://europepmc.org/articles/PMC352333/
