Zobrazeno 1 - 1
of 1
pro vyhledávání: '"T I, Jack"'
Autor:
D B, Judd, M D, Dowle, D, Middlemiss, D I, Scopes, B C, Ross, T I, Jack, M, Pass, E, Tranquillini, J E, Hobson, T A, Panchal
Publikováno v:
Journal of Medicinal Chemistry. 37:3108-3120
We have identified GR138950, a potent antagonist of the angiotensin II receptor with high oral bioavailability, as our second drug candidate to GR117289. Using GR117289, a compound with moderate bioavailability (20%) in man as a lead, we pursued a st