Zobrazeno 1 - 10
of 152
pro vyhledávání: '"T Hillmer"'
Autor:
Terril L. Verplaetse, Ansel T. Hillmer, Shivani Bhatt, Aleksandra Rusowicz, Songye Li, Nabeel Nabulsi, David Matuskey, Yiyun Huang, Sherry A. McKee, Kelly P. Cosgrove
Publikováno v:
Neurobiology of Stress, Vol 29, Iss , Pp 100609- (2024)
Background: Stress is a potent activator of the hypothalamic-pituitary-adrenal (HPA) axis, initiating the release of glucocorticoid hormones, such as cortisol. Alcohol consumption can lead to HPA axis dysfunction, including altered cortisol levels. U
Externí odkaz:
https://doaj.org/article/0e5254c826914c02b8944e6a0e091633
Autor:
Stephen R. Baldassarri, Ruth H. Asch, Ansel T. Hillmer, Robert H. Pietrzak, Nicole DellaGioia, Irina Esterlis, Margaret T. Davis
Publikováno v:
Chronic Stress, Vol 7 (2023)
Metabotropic glutamate receptor 5 (mGluR5) dysregulation has been implicated in the pathophysiology of many psychiatric disorders, as well as nicotine use and dependence. We used positron emission tomography with [ 18 F]FPEB to measure mGluR5 availab
Externí odkaz:
https://doaj.org/article/44fa536956e44c859b79412a36376fff
Autor:
Kelly Smart, Ashley Yttredahl, Maria A. Oquendo, J. John Mann, Ansel T. Hillmer, Richard E. Carson, Jeffrey M. Miller
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Preclinical studies have implicated kappa opioid receptors (KORs) in stress responses and depression-related behaviors, but evidence from human studies is limited. Here we present results of a secondary analysis of data acquired using positr
Externí odkaz:
https://doaj.org/article/441a7b9029424e3c8bf9ec359a4e5342
Autor:
Shivani Bhatt, Ansel T. Hillmer, Matthew J. Girgenti, Aleksandra Rusowicz, Michael Kapinos, Nabeel Nabulsi, Yiyun Huang, David Matuskey, Gustavo A. Angarita, Irina Esterlis, Margaret T. Davis, Steven M. Southwick, Matthew J. Friedman, Traumatic Stress Brain Study Group, Ronald S. Duman, Richard E. Carson, John H. Krystal, Robert H. Pietrzak, Kelly P. Cosgrove
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Neuroinflammation has been proposed to accompany the peripheral inflammation observed in PTSD. Here, authors find lower in vivo and postmortem levels of neuroimmune marker TSPO (translocator protein) in PTSD, in association with greater PTSD severity
Externí odkaz:
https://doaj.org/article/bb3f714c9295424b9a341b4b01971c9e
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-6 (2020)
Abstract Background Lipopolysaccharide (LPS) is a classic immune stimulus. LPS combined with positron emission tomography (PET) 18 kDa translocator protein (TSPO) brain imaging provides a robust human laboratory model to study neuroimmune signaling.
Externí odkaz:
https://doaj.org/article/20129abec91f48a3b53181e745cc69b3
Autor:
Adam P. Mecca, Kelly Rogers, Zachary Jacobs, Julia W. McDonald, Hannah R. Michalak, Nicole DellaGioia, Wenzhen Zhao, Ansel T Hillmer, Nabeel Nabulsi, Keunpoong Lim, Jim Ropchan, Yiyun Huang, David Matuskey, Irina Esterlis, Richard E. Carson, Christopher H. van Dyck
Publikováno v:
NeuroImage, Vol 238, Iss , Pp 118217- (2021)
Objective: Metabotropic glutamate receptor subtype 5 (mGluR5) is integral to the brain glutamatergic system and cognitive function. This study investigated whether aging is associated with decreased brain mGluR5 availability. Methods: Cognitively nor
Externí odkaz:
https://doaj.org/article/e1f29b61815d49eb8468baa6a3682fc6
Autor:
Xiaotian T. Fang, Takuya Toyonaga, Ansel T. Hillmer, David Matuskey, Sophie E. Holmes, Rajiv Radhakrishnan, Adam P. Mecca, Christopher H. van Dyck, Deepak Cyril D'Souza, Irina Esterlis, Patrick D. Worhunsky, Richard E. Carson
Publikováno v:
NeuroImage, Vol 237, Iss , Pp 118167- (2021)
Background: The human brain is inherently organized into distinct networks, as reported widely by resting-state functional magnetic resonance imaging (rs-fMRI), which are based on blood-oxygen-level-dependent (BOLD) signal fluctuations. 11C-UCB-J PET
Externí odkaz:
https://doaj.org/article/b6b00d2267484fc6a95d9f716fc52528
Publikováno v:
Seminars in Nuclear Medicine. 53:213-229
The brain's immune system plays a critical role in responding to immune challenges and maintaining homeostasis. However, dysregulated neuroimmune function contributes to neurodegenerative disease and neuropsychiatric conditions. In vivo positron emis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57678d22bc7a064fd6b43648cd115efc
https://doi.org/10.1053/j.semnuclmed.2022.08.008
https://doi.org/10.1053/j.semnuclmed.2022.08.008
Autor:
Kelly Smart, Jean-Dominique Gallezot, Nabeel Nabulsi, David Labaree, Ming-Qiang Zheng, Yiyun Huang, Richard E. Carson, Ansel T. Hillmer, Patrick D. Worhunsky
Publikováno v:
NeuroImage, Vol 214, Iss , Pp 116762- (2020)
Development of medications selective for dopamine D2 or D3 receptors is an active area of research in numerous neuropsychiatric disorders including addiction and Parkinson’s disease. The positron emission tomography (PET) radiotracer [11C]-(+)-PHNO
Externí odkaz:
https://doaj.org/article/6060b4447c104dc2af2c09a295190ede
Autor:
Katina C. Calakos, Ansel T. Hillmer, Jon Mikael Anderson, Brittany LeVasseur, Stephen R. Baldassarri, Gustavo A. Angarita, David Matuskey, Michael Kapinos, Ming-Qiang Zheng, Yiyun Huang, Kelly P. Cosgrove
Publikováno v:
Neuropsychopharmacology. 48:683-689
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd9119cd02bdc0a305b4602064025aca
https://doi.org/10.1038/s41386-023-01535-1
https://doi.org/10.1038/s41386-023-01535-1