Zobrazeno 1 - 10
of 26
pro vyhledávání: '"T H Watts"'
Autor:
N. Finkelstein, R. M. Dayam, J. Law, R. Goetgebuer, G. Chao, K. T. Abe, M. Sutton, J. M. Stempak, D. Pereira, D. Croitoru, L. Acheampong, S. Rizwan, K. Rymaszewski, R. Milgrom, D. Ganatra, N. V. Batista, M. Girard, I. Lau, R. Law, M. Cheung, B. Rathod, J. Kitaygorodsky, R. Samson, Q. Hu, N. Haroon, R. Inman, V. Piguet, M. Silverberg, A. C. Grigras, T. H. Watts, V. Chandran
Publikováno v:
Annals of the Rheumatic Diseases. 81:938-939
BackgroundThe impact of immunosuppressants on COVID-19 vaccination response and durability in patients with immune-mediated inflammatory diseases (IMID) is yet to be fully characterized. Humoral response may be attenuated in these patients especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b07ec8e38a4d08f9d6ab090b622624
https://doi.org/10.1136/annrheumdis-2022-eular.1667
https://doi.org/10.1136/annrheumdis-2022-eular.1667
Publikováno v:
The Journal of Immunology. 159:5871-5880
The role of cAMP/protein kinase A (PKA) in CD40 signal transduction is controversial, with evidence both for and against its importance. In this study we have used a tetracycline-repressible expression system to reversibly express a dominant-negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c732cde77ff7c676958ec8b071409b7
https://doi.org/10.4049/jimmunol.159.12.5871
https://doi.org/10.4049/jimmunol.159.12.5871
Publikováno v:
The Journal of Immunology. 158:3081-3089
The costimulatory receptor CD28 is important in the development of both Th1 and Th2 responses. To further assess the requirement for CD28 in the development of Th1 and Th2 responses, we analyzed the ability of T cells from wild-type or CD28- mice to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11e873690b3197541866fb34c1eb849a
https://doi.org/10.4049/jimmunol.158.7.3081
https://doi.org/10.4049/jimmunol.158.7.3081
Publikováno v:
The Journal of Immunology. 158:551-559
The interaction of the T cell surface protein CD28 with its ligand, B7-1 or B7-2, provides a critical costimulatory signal for T cell activation. T cells from CD28- mice are deficient in a variety of responses, including those to lectins and allogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa77c6fba7bd719d9470c61db8b36510
https://doi.org/10.4049/jimmunol.158.2.551
https://doi.org/10.4049/jimmunol.158.2.551
Publikováno v:
The Journal of Immunology. 157:2247-2255
T2 cells have a large homozygous deletion in the MHC II region. Transfection of MHC class II genes into T2 cells allows presentation of peptide but not native protein Ags. This defect in protein presentation has been attributed to the lack of HLA-DM,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8032530a7bd5271ceee6e8d89693ab81
https://doi.org/10.4049/jimmunol.157.6.2247
https://doi.org/10.4049/jimmunol.157.6.2247
Publikováno v:
International Immunology. 7:1585-1591
The region of invariant chain encompassing residues 81-104 is critical for association with MHC class II molecules. This segment of invariant chain, termed CLIP for Class II-associated invariant chain Peptides, has been shown to inhibit antigenic pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a52d18760c2bb2ab7b7b0786e38cd3f
https://doi.org/10.1093/intimm/7.10.1585
https://doi.org/10.1093/intimm/7.10.1585
Publikováno v:
The Journal of Immunology. 146:2952-2959
MHC proteins are polymorphic cell surface glycoproteins involved in the binding of peptide Ag and their presentation to T lymphocytes. The polymorphic amino acids of MHC proteins are primarily located in the N-terminal domains and are thought to infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22565b27055145b52e0c58e856b02a43
https://doi.org/10.4049/jimmunol.146.9.2952
https://doi.org/10.4049/jimmunol.146.9.2952
Publikováno v:
The Journal of Immunology. 145:3360-3366
The staphylococcal enterotoxins are a family of bacterial toxins that are thought to exert their pathogenic effects by the massive activation of T lymphocytes to produce lymphokines. Activation of T cells by these toxins is dependent on MHC class II+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d648f1e2180d2730b0c948788b7984d5
https://doi.org/10.4049/jimmunol.145.10.3360
https://doi.org/10.4049/jimmunol.145.10.3360
Publikováno v:
The Journal of Immunology. 144:1829-1834
The stability of a specific complex between the peptide Ag representing residue 323-339 of OVA and the MHC class II protein, I-Ad, in a lipid bilayer was investigated as a function of pH and temperature. The complex is much more stable in a lipid bil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08987d0f7a373a71a85e2ca54f079fff
https://doi.org/10.4049/jimmunol.144.5.1829
https://doi.org/10.4049/jimmunol.144.5.1829
Autor:
M A, DeBenedette, T, Wen, M F, Bachmann, P S, Ohashi, B H, Barber, K L, Stocking, J J, Peschon, T H, Watts
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(9)
4-1BB ligand (4-1BBL) is a member of the TNF family expressed on activated APC. 4-1BBL binds to 4-1BB (CD137) on activated CD4 and CD8 T cells and in conjunction with strong signals through the TCR provides a CD28-independent costimulatory signal lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9100bc30e0844036173855a3dbf1af5d
https://pubmed.ncbi.nlm.nih.gov/10528184
https://pubmed.ncbi.nlm.nih.gov/10528184