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Autor: M A, Stefater, T, Jenkins, T H, Inge

Publikováno v: Pediatric diabetes. 14(1)

Obesity is no longer just an adult disease. An increasing number of youth are overweight, defined as body mass index (BMI) at or greater than the 95th percentile for age (1). Between 2009 and 2010, 16.9% of children aged 2–19 yr were classified as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ceefbe7875b218b509cc934af4c2e37a
https://pubmed.ncbi.nlm.nih.gov/22830534

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Immunomodulatory effects of transforming growth factor-beta on T lymphocytes. Induction of CD8 expression in the CTLL-2 cell line and in normal thymocytes

Autor: T H Inge, K M McCoy, B M Susskind, S K Barrett, G Zhao, H D Bear

Publikováno v: The Journal of Immunology. 148:3847-3856

We investigated the role of transforming growth factor-beta 1 (TGF-beta) in regulation of T cell growth and differentiation. Treatment of CTLL-2 cells with TGF-beta inhibited IL-2-dependent proliferation and caused morphologic changes as well as incr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e164d5ac945b738c14ba5d0a9f01789e
https://doi.org/10.4049/jimmunol.148.12.3847

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gamma-Interferon plays a key role in T-cell-induced tumor regression

Autor: T M, Tuttle, C W, McCrady, T H, Inge, M, Salour, H D, Bear

Publikováno v: Cancer research. 53(4)

Recent studies have demonstrated that noncytolytic T-cells can mediate regression of murine tumors. In this report, we demonstrate that MCA-105 tumor-draining lymph node cells (DLN) activated with the protein kinase C activator, bryostatin 1, plus a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f6b461e6ac7c06c653a5bdff57a248b3
https://pubmed.ncbi.nlm.nih.gov/8428364

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Immunomodulatory effects of transforming growth factor-beta on T lymphocytes. Induction of CD8 expression in the CTLL-2 cell line and in normal thymocytes

Autor: T H, Inge, K M, McCoy, B M, Susskind, S K, Barrett, G, Zhao, H D, Bear

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 148(12)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a051247a99290fd4f87b0ec2aeca04a
https://pubmed.ncbi.nlm.nih.gov/1602133

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Inhibition of tumor-specific cytotoxic T-lymphocyte responses by transforming growth factor beta 1

Autor: T H, Inge, S K, Hoover, B M, Susskind, S K, Barrett, H D, Bear

Publikováno v: Cancer research. 52(6)

Transforming growth factor beta (TGF-beta) is a potent immunosuppressive cytokine that is produced by neoplastic and normal cells. It has not been demonstrated directly, however, that TGF-beta can inhibit antigen-specific T-cell responses to tumor ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32a55c2827df9ca53d13d8f0d6061b0b
https://pubmed.ncbi.nlm.nih.gov/1531782

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Activation and growth of murine tumor-specific T-cells which have in vivo activity with bryostatin 1

Autor: T M, Tuttle, T H, Inge, K P, Bethke, C W, McCrady, G R, Pettit, H D, Bear

Publikováno v: Cancer research. 52(3)

We examined the ability of bryostatin 1 (Bryo), a novel protein kinase C activator, plus ionomycin (Io), a calcium ionophore, to activate T-cells with specific antitumor activity. Lymphocytes from the draining lymph nodes (DLN) of MCA-105 tumor-beari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f2548944d7c7a331f4cd9b33a4b8ff49
https://pubmed.ncbi.nlm.nih.gov/1732041

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