Zobrazeno 1 - 10
of 30
pro vyhledávání: '"T H, Roderick"'
Autor:
D. Howell, Steven Nusinowitz, Norm L. Hawes, Ronald E. Hurd, T H Roderick, J. Wang, John R. Heckenlively, Muriel T. Davisson, Bo Chang
Publikováno v:
Visual Neuroscience. 22:587-593
The Jackson Laboratory, having the world's largest collection of mouse mutant stocks and genetically diverse inbred strains, is an ideal place to discover genetically determined eye variations and disorders. In this paper, we list and describe mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb69fd2c14f73346b516d48d3146ca9
https://doi.org/10.1017/s0952523805225075
https://doi.org/10.1017/s0952523805225075
Autor:
K B Gunning, Colin L. Stewart, L E Mobraaten, A C Schroeder, Makoto Mark Taketo, R R Fox, C T Hansen, F Lilly, G Hanten, T H Roderick
Publikováno v:
Proceedings of the National Academy of Sciences. 88:2065-2069
FVB/N mice offer a system suitable for most transgenic experiments and subsequent genetic analyses. The inbred FVB/N strain is characterized by vigorous reproductive performance and consistently large litters. Moreover, fertilized FVB/N eggs contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa93c2c5bd0e679b27eea54e5c27d57d
https://doi.org/10.1073/pnas.88.6.2065
https://doi.org/10.1073/pnas.88.6.2065
Publikováno v:
Genetica. 110(3)
We found high narrow-sense heritability of life span based on the regression of offspring on average parental (midparent) life spans. In two mouse populations prepared using the 4-way-cross design, mean +/- SE heritabilities were 62 +/- 11% (P0.001)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f7464893ea509eb89da5be3e115af10
https://pubmed.ncbi.nlm.nih.gov/11766841
https://pubmed.ncbi.nlm.nih.gov/11766841
Autor:
N L, Hawes, B, Chang, G S, Hageman, S, Nusinowitz, P M, Nishina, B S, Schneider, R S, Smith, T H, Roderick, M T, Davisson, J R, Heckenlively
Publikováno v:
Investigative ophthalmologyvisual science. 41(10)
To characterize the genetics and phenotype of a new mouse mutant with retinal degeneration, rd6, that is associated with extensive, scattered, small white retinal dots seen ophthalmoscopically.The phenotype was characterized using ophthalmoscopy, fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::471698085d4b73d0ba8dd84d8f0e4055
https://pubmed.ncbi.nlm.nih.gov/10967077
https://pubmed.ncbi.nlm.nih.gov/10967077
Autor:
B, Chang, N L, Hawes, T H, Roderick, R S, Smith, J R, Heckenlively, J, Horwitz, M T, Davisson
Publikováno v:
Molecular vision. 5
The mouse lop18 (lens opacity 18) mutation causes a white cataract obvious at weaning age. It soon progresses to a large white nuclear cataract with mild cortical changes. The mutation maps to mouse Chromosome 17 in close linkage to the alphaA-crysta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9acfef6e4dc5100fd6e114073367156
https://pubmed.ncbi.nlm.nih.gov/10493778
https://pubmed.ncbi.nlm.nih.gov/10493778
Autor:
S W, John, R S, Smith, O V, Savinova, N L, Hawes, B, Chang, D, Turnbull, M, Davisson, T H, Roderick, J R, Heckenlively
Publikováno v:
Investigative ophthalmologyvisual science. 39(6)
To characterize ocular abnormalities associated with iris atrophy in DBA/2J mice and to determine whether mice of this strain develop elevated intraocular pressure (IOP) and glaucoma.Different approaches, including slit-lamp biomicroscopy, ophthalmos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be1237af98a2f4e184fa0b39eb134a46
https://pubmed.ncbi.nlm.nih.gov/9579474
https://pubmed.ncbi.nlm.nih.gov/9579474
Autor:
R S, Smith, N L, Hawes, S D, Kuhlmann, J R, Heckenlively, B, Chang, T H, Roderick, J P, Sundberg
Publikováno v:
Investigative ophthalmologyvisual science. 37(2)
To describe a new mouse model of corneal surface disease and neovascularization.Anatomic changes were demonstrated in corn1 and control A.By/SnJ mice from day 10 of gestation of 8 months of age by routine techniques of light microscopic and scanning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccf1291e1685c29c3d97889e0d8b34ae
https://pubmed.ncbi.nlm.nih.gov/8603845
https://pubmed.ncbi.nlm.nih.gov/8603845
Publikováno v:
Growth, development, and aging : GDA. 59(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a3bf76b68982d9548aeeda6030c0a34
https://pubmed.ncbi.nlm.nih.gov/8675370
https://pubmed.ncbi.nlm.nih.gov/8675370
Publikováno v:
Laboratory animal science. 44(6)
Although microphthalmia and anophthalmia develop in many animals, they are a consistent and frequent finding in inbred and congenic strains of C57BL mice. Many investigators fail to take account of an incidence that may be as high as 12%, and this ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0201d3bbd4e33a5e390380003ca7e19f
https://pubmed.ncbi.nlm.nih.gov/7898027
https://pubmed.ncbi.nlm.nih.gov/7898027
Publikováno v:
Investigative ophthalmologyvisual science. 35(3)
To evaluate the retinal degeneration of the motor neuron degeneration (mnd) mouse, and to confirm its inheritance pattern and gene location.In screening the mnd/mnd mouse for ocular disease, a retinal degeneration was found that was evaluated by seri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3348db29e87031877fdadab695bcc3cd
https://pubmed.ncbi.nlm.nih.gov/8125718
https://pubmed.ncbi.nlm.nih.gov/8125718