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pro vyhledávání: '"T G Stinchcomb"'
Autor:
T G, Stinchcomb, J C, Roeske
Publikováno v:
Medical physics. 26(9)
In a recent paper [J. Nucl. Med. 38, 1923-1929 (1997)], the authors presented a dosimetry system which combines the computational ease of the MIRD schema with additional information provided by microdosimetry for use with alpha-particle emitters. In
Autor:
J C, Roeske, T G, Stinchcomb
Publikováno v:
Radiation research. 151(1)
In evaluating the efficacy of alpha-particle emitters, a cell survival curve is often determined for a particular source-target configuration. Investigators often wish to use this information about survival for a different source-target configuration
Autor:
J C, Roeske, T G, Stinchcomb
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(12)
Alpha-particle emitters are currently being considered for the treatment of metastatic disease. However, the dosimetry of alpha-particle emitters is a challenge because the dimensions of subcellular targets (e.g., the cell nucleus) are of the same or
Autor:
J C, Roeske, T G, Stinchcomb
Publikováno v:
Radiation research. 145(3)
Cell survival studies are a means of quantifying the biological effects of radiation. However, for alpha-particle sources, the dose-response relationship is complicated by the dominance of microdosimetric effects. In this work, we relate observed cel
Autor:
T G, Stinchcomb, J C, Roeske
Publikováno v:
Radiation research. 140(1)
A previous analysis of non-stochastic dose (Jostes et al., Radiat. Res. 127, 211-219, 1991; Schwartz et al., Health Phys. 62, 458-461, 1992) based on data obtained during irradiations of C-18 cells in suspension by alpha particles emitted from two fo
Autor:
T G, Stinchcomb, J C, Roeske
Publikováno v:
Medical physics. 19(6)
Analytic microdosimetry using Fourier transform techniques has been applied to internal alpha emitters. These techniques need revision and simplification for use with short-lived radionuclides such as those which may be useful for radioimmunotherapy.
Autor:
T. G. Stinchcomb, J. C. Roeske
Publikováno v:
Radiation Research. 141:346
Autor:
T G Stinchcomb, T B Borak
Publikováno v:
Physics in Medicine and Biology. 24:18-36
A rapid system has been developed for computing charged-particle distributions generated in tissue by any neutron spectra less than 4 MeV. Oxygen and carbon recoils are derived form R-matrix theory, and hydrogen recoils are obtained from cross-sectio
Autor:
Robert M. St John, T. G. Stinchcomb
Publikováno v:
Physics Today. 29:15-88
Autor:
T G, Stinchcomb, T B, Borak
Publikováno v:
Radiation research. 93(1)
Charged-particle production by neutrons and the resulting energy-deposition spectra in micron-sized spheres of tissue of varying diameters were calculated from thermal energies to 4 MeV. These data were used to obtain dose-average values of several q