Zobrazeno 1 - 9
of 9
pro vyhledávání: '"T G Altuntas"'
Autor:
T. G. Altuntas, Nevin Erk
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 27:83-93
A simple, specific, and accurate high performance liquid chromatographic (HPLC) method for determination of atorvastatin in bulk drug, tablets, and human plasma have been developed. Liquid chromatography was performed on a RP‐Supelcosil C18 (5 µm,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cac75315e4385ac306991453ef5878dd
https://doi.org/10.1081/jlc-120027087
https://doi.org/10.1081/jlc-120027087
Autor:
J W Gorrod, T G Altuntas
Publikováno v:
Drug metabolism and drug interactions. 13(4)
Factors affecting the metabolism of 2-amino-3-methylpyridine (2A3MP) in vitro have been studied and the conditions which allow maximal metabolism established. Ring nuclear and methyl hydroxylation, and 1-N-oxidation of 2A3MP were linear with respect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a5e9408088a7ac05c832e1bc964e4e
https://pubmed.ncbi.nlm.nih.gov/21568805
https://pubmed.ncbi.nlm.nih.gov/21568805
Autor:
N, Erk, T G, Altuntas
Publikováno v:
Die Pharmazie. 59(6)
Two different UV spectrophotometric methods were developed for the determination of rofecoxib in bulk form and in pharmaceutical formulations. The first method, an UV spectrophotometric procedure, was based on the linear relationship between the rofe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba51bbd42c124d4291dff5741ce1c80b
https://pubmed.ncbi.nlm.nih.gov/15248460
https://pubmed.ncbi.nlm.nih.gov/15248460
Autor:
John W. Gorrod, T. G. Altuntas
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 22(4)
The in vitro metabolism of 2-hydroxylamino-3-methylpyridine has been investigated using arochlor 1254 pretreated rat S9 mixtures. 2-Hydroxylamino-3-methylpyridine is rapidly converted to the parent amine 2-amino-3-methylpyridine. No further oxidation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6aaf628075627d08f0992b54514c932
https://pubmed.ncbi.nlm.nih.gov/9512932
https://pubmed.ncbi.nlm.nih.gov/9512932
Autor:
T G, Altuntas, J W, Gorrod
Publikováno v:
Anticancer research. 17(6D)
The metabolism of 2-amino-3-methylpyridine (2A3MP) in vitro has been investigated using the rat, rabbit, dog, marmoset, guinea pig and hamster hepatic microsomes and S9 supernatants (10,000 g fraction). Species differences were observed in the in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de46d2c3699bb4a342ce4de7a1eb55c4
https://pubmed.ncbi.nlm.nih.gov/9494554
https://pubmed.ncbi.nlm.nih.gov/9494554
Publikováno v:
Anticancer research. 17(5A)
The metabolism of the comutagen 2-amino-3-methylpyridine has been studied in vitro using rat and rabbit hepatic preparations. 2-Amino-3-methylpyridine-N-oxide, 2-amino-3-hydroxymethylpyridine and 2-amino-5-hydroxy-3-methylpyridine were formed by both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92491b5ee09573e7774b586ac9065033
https://pubmed.ncbi.nlm.nih.gov/9413192
https://pubmed.ncbi.nlm.nih.gov/9413192
Autor:
T. G. Altuntas, J. W. Gorrod
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 27(11)
1. The effects of various potential inhibitors, activators and inducers on the metabolism of the comutagen 2-amino-3-methylpyridine (2A3MP) by rabbit hepatic microsomes and S9 supernatants have been studied. 2. The 1-N-oxidation of 2A3MP to 2-amino-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced28270e5950ec44f79846b34c741d7
https://pubmed.ncbi.nlm.nih.gov/9413914
https://pubmed.ncbi.nlm.nih.gov/9413914
Publikováno v:
Journal of Clinical Pharmacology; Mar2004, Vol. 44 Issue 3, p224-233, 10p
Publikováno v:
Journal de pharmacie de Belgique. 44(6)
Some 2-benzylbenzimidazole and 2-phenoxymethylbenzimidazole derivatives were synthesized and tested for in vitro tuberculostatic activity against Mycobacterium tuberculosis H 37 Rv. and human type wild strain (protocol n degrees.4186). The synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f07f3fc239156b3b8c84ff6bf0ebd6b2
https://pubmed.ncbi.nlm.nih.gov/2517303
https://pubmed.ncbi.nlm.nih.gov/2517303