Zobrazeno 1 - 10
of 17
pro vyhledávání: '"T G, Smart"'
Publikováno v:
British Journal of Pharmacology
Background and Purpose Although the stoichiometry of the major synaptic αβγ subunit-containing GABAA receptors has consensus support for 2α:2β:1γ, a clear view of the stoichiometry of extrasynaptic receptors containing δ subunits has remained
Publikováno v:
The Journal of Physiology. 478:75-86
1. Intracellular recordings from postnatal 2- to 12-day-old (P2-12) rat hippocampal CA3 pyramidal neurones exhibited spontaneous synaptic potentials mediated by GABAA receptors. These potentials can be separated on the basis of amplitude into two cla
Autor:
T, Manzke, M, Niebert, U R, Koch, A, Caley, S, Vogelgesang, A-M, Bischoff, S, Hülsmann, E, Ponimaskin, U, Müller, T G, Smart, R J, Harvey, D W, Richter
Publikováno v:
Schmerz (Berlin, Germany). 25(3)
To control the breathing rhythm the medullary respiratory network generates periodic salvo activities for inspiration, post-inspiration and expiration. These are under permanent modulatory control by serotonergic neurons of the raphe which governs th
Autor:
C M, Houston, T G, Smart
Publikováno v:
The European journal of neuroscience. 24(9)
The gamma-aminobutyric acid type A (GABA(A)) receptor is a pentameric ligand-gated ion channel responsible for fast synaptic inhibition in the brain. Phosphorylation of the GABA(A) receptor by serine/threonine protein kinases, at residues located in
Autor:
B. J. Krishek, T. G. Smart
It is now over 20 years since the seminal studies by John Gurdon and colleagues established that Xenopus Zaevis oocytes, when injected with messenger RNA (mRNA), were able after a period of incubation to translate the mRNA and appropriately synthesiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::173905dcf8b9dcef91d8e480a499841b
https://doi.org/10.1385/0-89603-311-2:259
https://doi.org/10.1385/0-89603-311-2:259
Autor:
M E, Wilkins, T G, Smart
Publikováno v:
Neuropharmacology. 43(6)
Redox reagents are thought to modulate gamma-Aminobutyric acid type A (GABA(A)) receptors by regulating the redox state of the N-terminal disulphide bridge. Examining the redox sensitivity of recombinant GABA(A) receptors in human embryonic kidney ce
Publikováno v:
The Journal of biological chemistry. 274(51)
Type A gamma-aminobutyric acid receptors (GABA(A)), the major sites of fast synaptic inhibition in the brain, are believed to be composed predominantly of alpha, beta, and gamma subunits. Although cell surface expression is essential for GABA(A) rece
Publikováno v:
The European journal of neuroscience. 11(8)
Mefenamic acid (MFA) has anti-convulsant and pro-convulsant effects in vivo, and has been shown to potentiate and inhibit GABAA (gamma-aminobutyric acid) receptors in vitro. In this study, whole-cell currents were recorded from Xenopus oocytes and hu
Publikováno v:
Molecular pharmacology. 49(3)
The ubiquitous distribution of gamma-aminobutyric acid A (GABAA) receptor beta subunits throughout the central nervous system is in accord with a vital role in receptor structure and function. Homomeric beta subunits have been reported to be either G
Autor:
S J, Moss, T G, Smart
Publikováno v:
International review of neurobiology. 39
The major excitatory and inhibitory amino acid receptors in the mammalian central nervous system are considered to be glutamate, gamma-aminobutyric acid type A (GABAA), and glycine receptors. These receptors are widely acknowledged to participated in