Zobrazeno 1 - 10
of 16
pro vyhledávání: '"T G, Mant"'
Publikováno v:
International Journal of Pharmaceutical Medicine. 16:129-132
The aims of this study were to investigate possible interactions between EchoGen, a transpulmonary contrast agent in development that vaporizes after injection, and sevoflurane, and to determine the safety of the co-administration of sevoflurane and
Publikováno v:
Journal of Antimicrobial Chemotherapy. 38:1023-1029
The single-dose tolerance and pharmacokinetics of clinafloxacin, a new fluoroquinolone antibacterial agent. were evaluated in healthy volunteers. Single oral doses of 25, 50, 100, and 200 mg were well tolerated. Adverse events after placebo and clina
Publikováno v:
Anesthesiology. 80:97-103
Background: ANQ 9040 is an experimental nondepolarizing neuromuscular relaxant. Initial investigations in animals had indicated a rapid onset of action comparable to that of succinylcholine. The purpose of this study was to assess the safety and pote
Autor:
V Glover, P S John-Smith, G Haywood, P Morrison, T G Mant, G R McClelland, B L Goodwi, S J Warrington, P Turner, M Sandler
Publikováno v:
Journal of Psychopharmacology. 5:82-91
The clinical pharmacology of the new reversible monoamine oxidase (MAO) inhibitor, moclobemide, was examined in three separate studies in healthy male volunteers. In a single oral dose study, moclobemide (25-150 mg) was rapidly absorbed from the gast
Publikováno v:
British journal of anaesthesia. 83(3)
Dexmedetomidine is a highly selective alpha 2-adrenoceptor agonist with anaesthetic-sparing effects. We have determined the pharmacodynamic and pharmacokinetic interactions between dexmedetomidine and isoflurane in volunteers. Nine male subjects were
Publikováno v:
Advances in experimental medicine and biology. 431
Autor:
E. M. Allen, A. B. Vassos, N. J. Hounslow, H. A. Simmonds, B. Singer, P. M. Davies, T. G. Mant
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461374565
The hyperuricaemia following fructose loading was first demonstrated by Perheen-tupa and Raivio in 1967 (1). Subsequent studies (reviewed in 2) established that this elevation of plasma and urine uric acid concentrations in humans followed the rapid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e031b8601f05a162593732a09fcd3bc
https://doi.org/10.1007/978-1-4615-5381-6_6
https://doi.org/10.1007/978-1-4615-5381-6_6
Autor:
J M, Glover, J M, Leeds, T G, Mant, D, Amin, D L, Kisner, J E, Zuckerman, R S, Geary, A A, Levin, W R, Shanahan
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(3)
Healthy male volunteers received single or multiple intravenous infusions of an intercellular adhesion molecule-1 antisense phosphorothioate oligodeoxynucleotide, ISIS 2302, in a rising-dose (0.06-2.00 mg/kg infused over 2 hr), double-blind, placebo-
Publikováno v:
Thrombosis and haemostasis. 77(1)
Plasma pharmacokinetics, effect on coagulation parameters, and safety and tolerability of an intravenous infusion of REVASC before, during and after a DDAVP infusion were investigated. Twelve healthy volunteers were given an intravenous bolus dose fo
Publikováno v:
Adverse drug reactions and acute poisoning reviews. 9(3)