Zobrazeno 1 - 10
of 64
pro vyhledávání: '"T G, Lugo"'
Publikováno v:
Molecular and Cellular Biology. 10:2660-2668
Extinction of phosphoenolpyruvate carboxykinase (PCK) gene expression in hepatoma x fibroblast hybrids is mediated by a trans-acting genetic locus designated tissue-specific extinguisher 1 (TSE1). To identify PCK gene sequences required for extinctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1671cc18d269cabecab744bc26fbcfcc
https://doi.org/10.1128/mcb.10.6.2660
https://doi.org/10.1128/mcb.10.6.2660
Publikováno v:
Cancer research. 56(19)
Considerable molecular genetic and cytogenetic evidence indicates that chromosome 11 is a target for chromosome breakage, rearrangement, and loss during the development of human malignant melanomas. Abnormalities of the long arm of chromosome 11 are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b8001fed3510d1685abed9a6bfbc15c
https://pubmed.ncbi.nlm.nih.gov/8813145
https://pubmed.ncbi.nlm.nih.gov/8813145
Publikováno v:
Cancer research. 56(7)
Breaks and deletions of chromosome 6 are among the most frequent karyotypic abnormalities that appear in human malignant melanoma cells, and chromosome transfer experiments have provided functional evidence for the presence of a melanoma tumor suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41135e02b87f1116a1a24b347632cab0
https://pubmed.ncbi.nlm.nih.gov/8603413
https://pubmed.ncbi.nlm.nih.gov/8603413
Autor:
M E, Miele, G, Robertson, J H, Lee, A, Coleman, C T, McGary, P B, Fisher, T G, Lugo, D R, Welch
Publikováno v:
Molecular carcinogenesis. 15(4)
Progression of human melanoma toward increasing malignant behavior is associated with several nonrandom chromosomal aberrations, most commonly involving chromosomes 1, 6, 7, 9, and 10. We previously showed that introduction of human chromosome 6 into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b32334933f66f4926cb04c38e6cb354d
https://pubmed.ncbi.nlm.nih.gov/8634087
https://pubmed.ncbi.nlm.nih.gov/8634087
Publikováno v:
Receptor. 5(1)
The development of malignant melanoma is accompanied by an accumulation of genetic damage that is evident within tumor cells at both cytogenetic and molecular levels, and mutations at several gene loci are thought to contribute to malignant progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09e1f171556c58a6e32a04704768f98b
https://pubmed.ncbi.nlm.nih.gov/7613487
https://pubmed.ncbi.nlm.nih.gov/7613487
Publikováno v:
Cancer research. 54(2)
Deletions of DNA on chromosome 9p21-22 are frequently observed in cells derived from melanomas, gliomas, non-small cell lung cancers, and acute lymphoblastic leukemia. The minimal deletion shared by the latter three cancers extends from the interfero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2d1d9100755f511b293ed737754792a
https://pubmed.ncbi.nlm.nih.gov/8275465
https://pubmed.ncbi.nlm.nih.gov/8275465
Autor:
C Bender, Gavin P. Robertson, E K Goldberg, Gregory J. Walker, J F Flores, E You, Nicholas K. Hayward, P Jones, Jane W. Fountain, J M Glendening, M Gonzalgo, T G Lugo
Publikováno v:
Melanoma Research. 7:S37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b5a4dcb97f73ec40451b3ef7cf7b6ac
https://doi.org/10.1097/00008390-199706001-00128
https://doi.org/10.1097/00008390-199706001-00128
Publikováno v:
Journal of Biological Chemistry. 259:12161-12169
cAMP stimulates the transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) in rat liver. We have investigated the nucleotide sequences required for regulation of PEPCK gene expression by cAMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c8a98e4ce905ebfb68758d245e38448
https://doi.org/10.1016/s0021-9258(20)71334-7
https://doi.org/10.1016/s0021-9258(20)71334-7
Publikováno v:
Biochemical Genetics. 22:201-213
The photosensitivity of bromodeoxyuridine (BrdU)-substituted cells is known to be markedly enhanced by the fluorochrome Hoechst 33258. Since the incorporation of BrdU into nucleic acids depends upon its prior phosphorylation via thymidine kinase (TK;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978fce64d129a049f09d620b0e3a220f
https://doi.org/10.1007/bf00484224
https://doi.org/10.1007/bf00484224
Autor:
Owen N. Witte, T. G. Lugo
Publikováno v:
Molecular and Cellular Biology. 9:1263-1270
The tyrosine kinase P210 is the gene product of the rearranged BCR-ABL locus on the Philadelphia chromosome (Ph1), which is found in leukemic cells of patients with chronic myelogenous leukemia. It has a weakly oncogenic effect in immature murine hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cbe7ed861f7183c833305dd325ffc5c
https://doi.org/10.1128/mcb.9.3.1263
https://doi.org/10.1128/mcb.9.3.1263