The HRAS1 minisatellite locus and risk of ovarian cancer

Autor: J N, Weitzel, S, Ding, G P, Larson, R A, Nelson, A, Goodman, E C, Grendys, H G, Ball, T G, Krontiris

Publikováno v: Cancer research. 60(2)

Approximately 10% of ovarian cancers are due to mutations in highly penetrant inherited cancer susceptibility genes. The highly polymorphic HRAS1 minisatellite locus, located just downstream from the proto-oncogene H-ras-1 on chromosome 11p, consists

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a4029c653489db9b09c9a50649ab56c
https://pubmed.ncbi.nlm.nih.gov/10667571

Association of rare alleles of the Harvey ras protooncogene locus with lung cancer

Autor: H, Sugimura, N E, Caporaso, R V, Modali, R N, Hoover, J H, Resau, B F, Trump, J A, Longergan, T G, Krontiris, D L, Mann, A, Weston

Publikováno v: Cancer research. 50(6)

The hypothesis that rare variable nucleotide tandem repeat alleles of the Ha-ras-1 polymorphism are an inherited predisposing factor in human lung carcinogenesis has been evaluated in an age, race, and smoking matched case-control study. Twenty-three

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3e81047913a051075853579e985b6e0
https://pubmed.ncbi.nlm.nih.gov/2407346

Oncogenes

Autor: M, Colb, T G, Krontiris

Publikováno v: Advances in internal medicine. 31

Many of the genes that are likely participants in the pathogenesis of human neoplasia have been identified. The major classes of events that activate these genes in tumors have also been described. We expect that continuing research on the function o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd7160ef9abf463c49e245f963d86752
https://pubmed.ncbi.nlm.nih.gov/3004124

Clonal analysis of untreated non-Hodgkin's lymphoma utilizing immunoglobulin gene rearrangement and immunophenotype

Autor: R A, Rudders, S, Dhillon, T G, Krontiris

Publikováno v: Cancer research. 48(22)

We have prospectively examined 66 consecutive initial diagnostic lymph node biopsies from unselected patients suspected of having malignant lymphoma for clonal immunophenotypic and immunogenotypic markers. By morphological and cell surface phenotypic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::010032008cda6cb5dd29e9ea65630a93
https://pubmed.ncbi.nlm.nih.gov/3263184

Characterizing the Conformational Dynamics of Human SUMO2: Insights into its Interaction with Metal Ions and SIMs.

Autor: Kaur A; Department of Chemistry, Guru Nanak Dev University, Amritsar, 143005, Punjab, India.; Present address: Institute for Bioscience and Biotechnology Research, University of Maryland & National Institute of Standards and Technology, United States., Singh H; Department of Chemistry, Guru Nanak Dev University, Amritsar, 143005, Punjab, India., Kumar D; Centre of Biomedical Research, Sanjay Gandhi Post-Graduate Institute of Medical Sciences Campus, Raebareli Road, Lucknow, 226014, Uttar Pradesh, India., Gahlay GK; Department of Molecular Biology and Biochemistry, Guru Nanak Dev University, Amritsar, 143005, Punjab, India., Mithu VS; Department of Chemistry, Guru Nanak Dev University, Amritsar, 143005, Punjab, India.; Present address: Department of NMR-based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Am Faßberg 11, Göttingen, 37077, Germany.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Jun 03; Vol. 25 (11), pp. e202400045. Date of Electronic Publication: 2024 May 10.