Zobrazeno 1 - 9
of 9
pro vyhledávání: '"T G, Hamill"'
Autor:
M E, Duggan, L T, Duong, J E, Fisher, T G, Hamill, W F, Hoffman, J R, Huff, N C, Ihle, C T, Leu, R M, Nagy, J J, Perkins, S B, Rodan, G, Wesolowski, D B, Whitman, A E, Zartman, G A, Rodan, G D, Hartman
Publikováno v:
Journal of medicinal chemistry. 43(20)
Modification of the potent fibrinogen receptor (alpha(IIb)beta(3)) antagonist 1 generated compounds with high affinity for the vitronectin receptor alpha(v)beta(3). Sequential modification of the basic N-terminus of 1 led to the identification of the
Autor:
Z, Szabo, P F, Kao, H D, Burns, R E, Gibson, T G, Hamill, H T, Ravert, S E, Kim, W B, Mathews, J L, Musachio, U, Scheffel, R F, Dannals
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(7)
Antagonists of the angiotensin II AT1 receptor subtype have been recently introduced for treatment of arterial hypertension and for pharmacological studies of these receptors. The purpose of this work was to label such an antagonist with 11C and test
Autor:
R A, Bednar, S L, Gaul, T G, Hamill, M S, Egbertson, J A, Shafer, G D, Hartman, R J, Gould, B, Bednar
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(3)
A critical function of fibrinogen in hemostasis and thrombosis is to mediate platelet aggregation by binding selectively to an activated form of glycoprotein (GP) IIb/IIIa. Although numerous peptide and nonpeptide fibrinogen receptor antagonists have
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(3)
L-738,167 is a potent and long-acting fibrinogen receptor antagonist and may be useful for treatment of chronic thrombotic occlusive disorders. The purposes of this study were to characterize the metabolism and disposition of L-738,167, and to invest
Autor:
S E, Kim, U, Scheffel, Z, Szabo, H D, Burns, R E, Gibson, H T, Ravert, W B, Mathews, T G, Hamill, R F, Dannals
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 37(2)
Angiotensin II (ANG II) initiates a variety of physiological effects by binding to high affinity receptors. Two ANG II receptor subtypes, AT1 and AT2, have recently been identified. This study was undertaken to evaluate [11C]L-159,884, an AT1 subtype
Publikováno v:
Clinical Chemistry. 31:601-605
The European standardized method for measuring porphobilinogen synthase (PBGS, EC 4.2.1.24) activity in peripheral erythrocytes is widely used in epidemiological studies of low-level Pb absorption. We have modified it to include activation with dithi
Autor:
G. H. Posner, T. G. Hamill
Publikováno v:
ChemInform. 20
Publikováno v:
Clinical chemistry. 31(4)
The European standardized method for measuring porphobilinogen synthase (PBGS, EC 4.2.1.24) activity in peripheral erythrocytes is widely used in epidemiological studies of low-level Pb absorption. We have modified it to include activation with dithi
Publikováno v:
Chemischer Informationsdienst. 17