Zobrazeno 1 - 10
of 19
pro vyhledávání: '"T G, Christensen"'
Autor:
A-C Bay-Jensen, Cecilie Freja Kjelgaard-Petersen, M.A. Karsdal, T. G. Christensen, Per Hägglund, Christian S. Thudium
Publikováno v:
Abstracts Accepted for Publication.
Background It is important to establish translational methods that aid in pre-clinical go/no-go decision points to increase the success rate of approved DMARDs. The Spleen tyrosine kinase (Syk) inhibitor Fostamatinib (Fosta) was terminated for develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae1636dc014018bd1c90c80d65bec69e
https://doi.org/10.1136/annrheumdis-2017-eular.6788
https://doi.org/10.1136/annrheumdis-2017-eular.6788
Publikováno v:
Endothelium. 8:255-260
We have been studying the relationships between cell growth and the expression of the gap junction protein Connexin43 (Cx43) in cultured bovine aortic endothelial cells (BAEC). As part of these studies, we examined the effect of the growth inhibitory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebdfb2f28ef6c3a2584b79660efe47d
https://doi.org/10.3109/10623320109090802
https://doi.org/10.3109/10623320109090802
Publikováno v:
European Respiratory Journal. 4:205-209
The anti-inflammatory drug flurbiprofen speeds the repair of cigarette smoke-induced bronchial secretory cell metaplasia (SCM) in rats. We tested whether flurbiprofen would prevent or mitigate the development of elastase-induced bronchial SCM in hams
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2667e2715de59fce9ae57b262af8fda4
https://doi.org/10.1183/09031936.93.04020205
https://doi.org/10.1183/09031936.93.04020205
Autor:
Bodil-Cecilie Sondergaard, C. Chrtiansen, N. Schultz, T. G. Christensen, Natalie A. Sims, Morten A. Karsdal, Jonathan H. Gooi, Anne-Christine Bay-Jensen, S.H. Madsen
Publikováno v:
Bone. 44:S254
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a515f970325e9c30def4ffac578bb4ad
https://doi.org/10.1016/j.bone.2009.03.430
https://doi.org/10.1016/j.bone.2009.03.430
Autor:
E C, Lucey, P J, Stone, D E, Ciccolella, R, Breuer, T G, Christensen, R C, Thompson, G L, Snider
Publikováno v:
The Journal of laboratory and clinical medicine. 115(2)
Studies were undertaken to evaluate the in vitro properties of recombinant human secretory leukocyte-protease inhibitor (rSLPI) that had been made in Escherichia coli in an inactive form and refolded, and to determine whether emphysema and bronchial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4b7c514be5a4068cf9d023692196b70
https://pubmed.ncbi.nlm.nih.gov/2299266
https://pubmed.ncbi.nlm.nih.gov/2299266
Publikováno v:
Journal of Clinical Investigation. 59:397-404
A single intratracheal instillation of pancreatic elastase in hamsters induces a lesion resembling human panacinar emphysema. This paper reports the occurrence of irreversible goblet cell metaplasia in the bronchial epithelium of hamsters similarly e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d726dd5296897dc0d034edc8d3a75bd
https://doi.org/10.1172/jci108652
https://doi.org/10.1172/jci108652
Autor:
E C, Lucey, P J, Stone, R, Breuer, T G, Christensen, J D, Calore, A, Catanese, C, Franzblau, G L, Snider
Publikováno v:
The American review of respiratory disease. 132(2)
To determine whether purified human neutrophil cathepsin G (Cat-G) can act by itself or in concert with purified human neutrophil elastase (HNE) in the induction of emphysema and bronchial secretory cell metaplasia (SCM), we gave golden Syrian hamste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c19ed8dd4756e8db9335a29f8c35200
https://pubmed.ncbi.nlm.nih.gov/3849280
https://pubmed.ncbi.nlm.nih.gov/3849280
Autor:
G L, Snider, E C, Lucey, T G, Christensen, P J, Stone, J D, Calore, A, Catanese, C, Franzblau
Publikováno v:
The American review of respiratory disease. 129(1)
Purified human neutrophil elastase (HNE) and a crude extract of human neutrophils (EXT) were administered intratracheally to hamsters, and their effects were determined 21 and 56 days later by measurement of lung statics and dynamics and by light mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::995fb6dffb60ea1e6aca8ed78d4f904f
https://pubmed.ncbi.nlm.nih.gov/6561016
https://pubmed.ncbi.nlm.nih.gov/6561016
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 41(3)
In interstitial fibrosis of the lung, pulmonary vessels show priminent sclerotic changes. We have studied arteries in lung biopsies from patients with lung fibrosis of varied etiology using light and electron microscopy. It was found that the sclerot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e641b549f705a44b20761e3e0010e212
https://pubmed.ncbi.nlm.nih.gov/470345
https://pubmed.ncbi.nlm.nih.gov/470345