Zobrazeno 1 - 10
of 19
pro vyhledávání: '"T G, Brewer"'
Autor:
D. E. Kyle, M. A. Vane, Young Gd, M. Gettayacamin, H K Webster, J. M. Petras, T. G. Brewer, K. D. Corcoran, James O. Peggins, R. A. Bauman
Publikováno v:
Anatomy and Embryology. 201:383-397
Malaria poses a threat across several continents: Eurasia (Asia and parts of Eastern Europe), Africa, Central and South America. Bradley (1991) estimates human exposure at 2,073,000,000 with infection rates at 270,000,000, illnesses at 110,000,000, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fff254caa20944cfef93c4992702b0
https://doi.org/10.1007/s004290050326
https://doi.org/10.1007/s004290050326
Publikováno v:
Agronomy Journal. 86:823-828
To formulate strategies for controlling herbicide resistance in Italian ryegrass (Lolium multiflorum Lam.), the selective pressures acting on wild Italian ryegrass populations to encourage evolution of resistance must be identified. Field and greenho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bf8f7840082a21e029754f249d289bd
https://doi.org/10.2134/agronj1994.00021962008600050014x
https://doi.org/10.2134/agronj1994.00021962008600050014x
Publikováno v:
Annals of Tropical Medicine & Parasitology. 89:447-449
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a585011afba1a2706a52e5696e29ab4
https://doi.org/10.1080/00034983.1995.11812975
https://doi.org/10.1080/00034983.1995.11812975
Publikováno v:
Medecine tropicale : revue du Corps de sante colonial. 58
The discovery of the occult brainstem neurotoxicity subsequent to widespread deployment of artemisinin derivatives has created particular problems. That is, the clinical setting for artemisinin use is problematic for accomplishing what ordinarily wou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3a0ef0bcafa45b21ee7c3a6a6046e4d
https://pubmed.ncbi.nlm.nih.gov/10212893
https://pubmed.ncbi.nlm.nih.gov/10212893
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(6)
Penclomedine is a multi-chlorinated alpha-picoline derivative that has demonstrated activity in several murine breast cancer models and is currently in clinical testing for use against solid tumors. This study evaluates the metabolism of penclomedine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b22d460c8448624e3b6738ce64750841
https://pubmed.ncbi.nlm.nih.gov/9616185
https://pubmed.ncbi.nlm.nih.gov/9616185
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(4)
beta-Arteether (AE) is an endoperoxide sesquiterpene lactone derivative currently being developed for the treatment of severe, complicated malaria caused by multidrug-resistant Plasmodium falciparum. Studies were undertaken to determine which form(s)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25a9dfd3afc4fad9c194465af26b31f4
https://pubmed.ncbi.nlm.nih.gov/9531517
https://pubmed.ncbi.nlm.nih.gov/9531517
Publikováno v:
Pharmacology. 54(5)
Arteether (AE) is primarily deethylated to dihydroqinghaosu (DQHS) in rats and humans. Conversion of AE to DQHS was impaired in microsomes from rats infected with Plasmodium berghei. The Km for AE was 175.1 +/- 49.1 and 124.4 +/- 115.1 mumol/l, and V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a3d2894737cb6b48e158b3ad0adcca0
https://pubmed.ncbi.nlm.nih.gov/9380774
https://pubmed.ncbi.nlm.nih.gov/9380774
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(1)
The in vitro metabolism of the 8-aminoquinoline, 8-(4-amino-1- methylbutylamino-2,6-dimethoxy-4-methyl-5-(3-trifluromethyl- phenoxy)quinoline (WR 238605), by rat liver microsomes was studied. After incubation of WR 238605 with rat liver microsomes, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75887fab414c9b62711c86c65e700044
https://pubmed.ncbi.nlm.nih.gov/7720510
https://pubmed.ncbi.nlm.nih.gov/7720510
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(1)
Primaquine, 8-(4-amino-1-methylbutylamino)-6-methoxyquinoline, is an antimalarial 8-aminoquinoline derivative. Although it has been in use since 1952, its metabolism has not been clearly defined. This is due to the instability of the expected aminoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf88f5dcd41f821c48daf2f218483347
https://pubmed.ncbi.nlm.nih.gov/7720521
https://pubmed.ncbi.nlm.nih.gov/7720521
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 22(3)
Malaria is a major cause of health problems in a large portion of the world. The 8-aminoquinoline compound, primaquine, is one of the only compounds useful for relapses of Plasmodium vivax and Plasmodium ovale malaria. Primaquine has several toxiciti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e55c36612634495a9e9e79b65f73af4
https://pubmed.ncbi.nlm.nih.gov/8070311
https://pubmed.ncbi.nlm.nih.gov/8070311