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Autor: H, Ariffin, A, Geikowski, T F, Chin, D, Chau, A, Arshad, K, Abu Bakar, S, Krishnan

Publikováno v: The Medical journal of Malaysia. 69(4)

We report a case of Griscelli Syndrome (GS). Our patient initially presented with a diagnosis of haemophagocytic lymphistiocytosis (HLH). Subsequent microscopic analysis of the patient's hair follicle revealed abnormal distribution of melanosomes in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e112465b6812b15a83b65053ab807415
https://pubmed.ncbi.nlm.nih.gov/25500851

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Poisoning by Datura leaves used as edible wild vegetables

Autor: S S, Chang, M L, Wu, J F, Deng, C C, Lee, T F, Chin, S J, Liao

Publikováno v: Veterinary and human toxicology. 41(4)

The causes of Datura intoxication include medication overdose, misuse of edible vegetables, deliberate abuse as a hallucinogen, homicidal or robbery and accidental intoxication from contaminated food. We report an incident of 14 people with Datura in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::13b670c12d812d84e9e809867c9c857c
https://pubmed.ncbi.nlm.nih.gov/10434380

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The 14-3-3 proteins encoded by the BMH1 and BMH2 genes are essential in the yeast Saccharomyces cerevisiae and can be replaced by a plant homologue

Autor: G P, van Heusden, D J, Griffiths, J C, Ford, T F, Chin-A-Woeng, P A, Schrader, A M, Carr, H Y, Steensma

Publikováno v: European journal of biochemistry. 229(1)

The 14-3-3 proteins comprise a family of highly conserved acidic proteins. Several activities have been ascribed to these proteins, including activation of tyrosine and tryptophan hydroxylases in the presence of calcium/calmodulin-dependent protein k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ef8d6e83f95253e9a67589bba53e7a2c
https://pubmed.ncbi.nlm.nih.gov/7744048

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Structural effects on the binding of amine drugs with the diphenylmethyl functionality to cyclodextrins. II. A molecular modeling study

Autor: W Q, Tong, J L, Lach, T F, Chin, J K, Guillory

Publikováno v: Pharmaceutical research. 8(10)

Molecular modeling has been used to study the complexation between alpha, beta, or gamma-cyclodextrin (CD) and a group of amine compounds having the diphenylmethyl functionality. The computer program SYBYL 5.3 and the Tripos force field (version 5.2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b68bbdeb1c90f3c7ccf0270f9279feb3
https://pubmed.ncbi.nlm.nih.gov/1796050

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Structural effects on the binding of amine drugs with the diphenylmethyl functionality to cyclodextrins. I. A microcalorimetric study

Autor: W Q, Tong, J L, Lach, T F, Chin, J K, Guillory

Publikováno v: Pharmaceutical research. 8(7)

Solution calorimetry has been employed to evaluate the stability constants and enthalpy changes associated with complex formation between alpha-, beta, or gamma-cyclodextrin (CD) and a group of amine compounds having the diphenylmethyl functionality.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d1f2716d649c79a06937d5a0c6b7828
https://pubmed.ncbi.nlm.nih.gov/1924150

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Akademický článek

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Uridine-induced hyperthermia in the rabbit

Autor: T F Chin, J C Cradock, S K Ackerman, H D Hochstein, B R Vishnuvajjala

Publikováno v: Journal of Pharmacy and Pharmacology. 38:226-229

Uridine injection in 0.6% saline elevated rabbit temperatures (mean = 0.9 °C) in the USP XX pyrogen test. Hyperthermia was delayed in onset and peaking 3–4 h post injection, but the injection was negative in the limulus amoebocyte lysate (LAL) ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454b72a76eb6fe73e53c7d07652b6b19
https://doi.org/10.1111/j.2042-7158.1986.tb04552.x

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Drug diffusion and bioavailability: tetracycline metallic chelation

Autor: T F, Chin, J L, Lach

Publikováno v: American journal of hospital pharmacy. 32(6)

The effects of chelation on the in vitro diffusion rate of tetracycline at variable pH values and concentrations was studied. A two-compartment diffusion cell using a semipermeable cellophane membrane was used to determine diffusion rates. Tetracycli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6020c1a9aef046d4e6d23349748f0303
https://pubmed.ncbi.nlm.nih.gov/239596

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Theophylline pharmacokinetics in adolescent females following coadministration of oral contraceptives

Autor: G, Koren, T F, Chin, J, Correia, A, Tesoro, S M, MacLeod

Publikováno v: Clinical and investigative medicine. Medecine clinique et experimentale. 8(3)

The influence of 3-9 months of combined low dose oral contraceptives on theophylline pharmacokinetics was studied in 10 adolescent females (age 15-18 years, mean +/- SD 17 +/- 1) and compared to 10 age-matched control subjects (age 13.8-19 years, mea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f100a5b1f37d58b03da9028dc1983790
https://pubmed.ncbi.nlm.nih.gov/4042465

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