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Inhibition of activator protein 1 activity by paclitaxel suppresses interleukin-1-induced collagenase and stromelysin expression by bovine chondrocytes

Autor: A, Hui, W X, Min, J, Tang, T F, Cruz

Publikováno v: Arthritis and rheumatism. 41(5)

Cytokine-induced collagenase 1 (matrix metalloproteinase 1 [MMP-1]) and stromelysin 1 (MMP-3) expression is dependent on activator protein 1 (AP-1) activation and have a fundamental role in the pathophysiology of arthritic diseases by degrading conne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::10a3fb4d37178b41df4a1bde220f157b
https://pubmed.ncbi.nlm.nih.gov/9588740

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Interleukin-1 beta induction of c-fos and collagenase expression in articular chondrocytes: involvement of reactive oxygen species

Autor: Y Y, Lo, J A, Conquer, S, Grinstein, T F, Cruz

Publikováno v: Journal of cellular biochemistry. 69(1)

Interleukin-1 beta (IL-1) is implicated in cartilage destruction in arthritis through promotion of matrix metalloproteinase production. Upregulation of collagenase gene expression by IL-1 is known to require the transactivators Fos and Jun. Recently,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::07ee51631c0570792aea65d0b3ef7ed6
https://pubmed.ncbi.nlm.nih.gov/9513043

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Paclitaxel selectively induces mitotic arrest and apoptosis in proliferating bovine synoviocytes

Autor: A. Hui, Christopher A. McCulloch, W. L. Hunter, T. F. Cruz, Gajanan Kulkarni

Publikováno v: Arthritis and rheumatism. 40(6)

Objective. Rheumatoid arthritis (RA) is characterized by chronic progressive destruction of joints involving several disease processes, such as villous hypertrophy, proliferation of synovial lining cells, and infiltration of inflammatory cells. Synov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db27a65dc7cfc11c6bfe5cf010dd6164
https://pubmed.ncbi.nlm.nih.gov/9182918

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[Molecular mechanisms implicated in the inhibition of collagenase expression by diacerheine]

Autor: T F, Cruz, J, Tang, S, Pronost, J P, Pujol

Publikováno v: La Revue du praticien. 46(6 Spec)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d972766bff40d7e1a33081d2d0bb7989
https://pubmed.ncbi.nlm.nih.gov/8731725

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Effects of continuous passive motion and immobilization on synovitis and cartilage degradation in antigen induced arthritis

Autor: H K, Kim, R G, Kerr, T F, Cruz, R B, Salter

Publikováno v: The Journal of rheumatology. 22(9)

To determine the effects of continuous passive motion (CPM) and immobilization on synovitis and cartilage degradation in an experimental model of chronic inflammatory, antigen-induced arthritis.After bilateral arthritis induction of knee joints in 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5fb4db91bddd24d262550c29d385a174
https://pubmed.ncbi.nlm.nih.gov/8523351

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Effect of Mycoplasma arthritidis superantigen on enzymatically induced arthritis in mice

Autor: N. Hozumi, P. A. Quinn, R. A. Kandel, Cynthia A. Chambers, T. F. Cruz, H. Sustackova

SUMMARY The objective of this study was to examine the effect of the stimulation of the immune system with Mycoplasma arthritidis superantigen (MAS) on joint inflammation and cartilage destruction. MAS was administered either alone or combined with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8d81515efc022f36bad390ce276f38
https://europepmc.org/articles/PMC1534219/

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Calcium pyrophosphate dihydrate (CPPD) crystal dissolution by alkaline phosphatase: interaction of alkaline phosphatase on CPPD crystals

Autor: T, Shinozaki, Y, Xu, T F, Cruz, K P, Pritzker

Publikováno v: The Journal of rheumatology. 22(1)

As alkaline phosphatase (ALP) can dissolve calcium pyrophosphate dihydrate (CPPD) crystals, and as dissolution is facilitated when the enzyme is proximate to the crystals, we studied the mechanism of ALP interaction with CPPD crystals in vitro.ALP wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf1d97357bdf92072ea37a20d89cca8e
https://pubmed.ncbi.nlm.nih.gov/7699658

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Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes

Autor: J A, Conquer, S A, Jones, T F, Cruz

Publikováno v: Osteoarthritis and cartilage. 2(4)

Phorbol 12-myristate 13-acetate (PMA), interleukin-1 (IL-1) and lipopolysaccharide (LPS) induce similar responses in a variety of cell types, including chondrocytes. These responses include the release of arachidonic acid (AA) and the production of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c5b0c6d5ebf85219fec2c995ce825002
https://pubmed.ncbi.nlm.nih.gov/11550712

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Characterization of chondrocyte alkaline phosphatase as a potential mediator in the dissolution of calcium pyrophosphate dihydrate crystals

Autor: Y, Xu, K P, Pritzker, T F, Cruz

Publikováno v: The Journal of rheumatology. 21(5)

To characterize chondrocyte alkaline phosphatase (ALP) distribution and expression in cartilage and monolayer cultures.Sections of bovine articular cartilage or chondrocyte monolayer cultures were stained for ALP activity. Surface ALP was released wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::000500b5514318132e38e3d852a2dcfb
https://pubmed.ncbi.nlm.nih.gov/8064734

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