Zobrazeno 1 - 9
of 9
pro vyhledávání: '"T E Hesson"'
Publikováno v:
Hypertension. 4:86-95
Inactive renin was partially purified from 4.5 liters of human plasma (502-fold, specific activity 0.8 X 10(-3) Goldblatt units/mg protein) and from 207 g renal cortex (103-fold, 52 X 10(-3) Goldblatt units/mg). In contrast to active renin, inactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444f9e83f5418f798d0b1fb99035e4b3
https://doi.org/10.1161/01.hyp.4.3.86
https://doi.org/10.1161/01.hyp.4.3.86
Publikováno v:
Clinical and Experimental Hypertension. Part A: Theory and Practice. 4:2039-2047
Partially-purified inactive renins from human plasma and kidney seem to be identical in most respects except for apparent molecular size. To evaluate this difference, we determined apparent molecular weights by gel filtration with internal radiolabel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe8e134ed2a5344292fa816b3b8e680
https://doi.org/10.3109/10641968209062369
https://doi.org/10.3109/10641968209062369
Publikováno v:
Clinical Science. 59:29s-33s
1. Plasma prorenin (inactive renin), which accounts for about 70% of the total renin in human plasma, was almost completely separated from active renin by affinity chromatography on Cibacron blue F3G-A-agarose. The slight residual renin activity pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303d5f8a591230812c9d9953de1dc9eb
https://doi.org/10.1042/cs059029s
https://doi.org/10.1042/cs059029s
Publikováno v:
Clinical Science. 63:167s-170s
1. Purified inactive renin from human kidney or plasma was activated to a similar extent by incubation with trypsin or by dialysis to pH 3.3. 2. Trypsin- or acid-activated inactive renin was like active renal renin in terms of pH optimum (pH 5.5-6.0)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc8bbfae993a6247c082ab00eb2c77df
https://doi.org/10.1042/cs063167s
https://doi.org/10.1042/cs063167s
Autor:
M Aurell, Jean E. Sealey, M C Ruddy, B Dharmgrongartama, John H. Laragh, T E Hesson, Steven A. Atlas
Publikováno v:
The Journal of clinical investigation. 73(2)
Inactive renin comprises well over half the total renin in normal human plasma. There is a direct relationship between active and inactive renin levels in normal and hypertensive populations, but the proportion of inactive renin varies inversely with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6623b3e9e14b36e6d05c7599dee57a99
https://pubmed.ncbi.nlm.nih.gov/6365974
https://pubmed.ncbi.nlm.nih.gov/6365974
Publikováno v:
Clinical and experimental hypertension. Part A, Theory and practice. 4(11-12)
For human samples quantitation of inactive renin can be carried out by incubation with trypsin under defined conditions, followed by RIA of the activated renin. For dog samples we were unable to obtain evidence for the presence of inactive renin in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef593846943ad37d228ef5443d8bfc23
https://pubmed.ncbi.nlm.nih.gov/6756690
https://pubmed.ncbi.nlm.nih.gov/6756690
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 3(3 Pt 2)
Estimation of apparent molecular weight (mw) of inactive renin by gel filtration of human plasma was found to be inaccurate when "acid activation" or "cryoactivation" was used for detection; recoveries were only 5% to 20%. Trypsin activation produced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68505c275f5973ca5dc7b1b8af6ac579
https://pubmed.ncbi.nlm.nih.gov/7021414
https://pubmed.ncbi.nlm.nih.gov/7021414
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 4(3 Pt 2)
Inactive renin was partially purified from 4.5 liters of human plasma (502-fold, specific activity 0.8 X 10(-3) Goldblatt units/mg protein) and from 207 g renal cortex (103-fold, 52 X 10(-3) Goldblatt units/mg). In contrast to active renin, inactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8e772441683846799e39906d53b99f8
https://pubmed.ncbi.nlm.nih.gov/7040242
https://pubmed.ncbi.nlm.nih.gov/7040242
Publikováno v:
Biochemical and biophysical research communications. 132(3)
Antibody raised to a synthetic dodecapeptide, corresponding to the C-terminal portion of the human renin pro-segment, was tested for its ability to recognize highly purified human inactive or active (mature) renins; immune complexes were detected by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f7216612b0a0c7298cbdd8fd3f6c23
https://pubmed.ncbi.nlm.nih.gov/3907628
https://pubmed.ncbi.nlm.nih.gov/3907628