Zobrazeno 1 - 10
of 13
pro vyhledávání: '"T E Chagwedera"'
Autor:
T E Chagwedera, A. Douglas Kinghorn, Heebyung Chai, Daniel Chávez, Qi Gao, Geoffrey A. Cordell, Norman R. Farnsworth, John M. Pezzuto
Publikováno v:
Tetrahedron Letters. 42:3685-3688
Four novel stilbenes ( 1 – 4 ) were isolated from the root bark of Ekebergia benguelensis . The structures were established by spectroscopic methods including 2D NMR analysis. The structure of 1 , a new stilbene–coumarin hybrid representing a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c184df4b14ad56a9603d38199a7b9295
https://doi.org/10.1016/s0040-4039(01)00560-3
https://doi.org/10.1016/s0040-4039(01)00560-3
Autor:
Norman R. Farnsworth, Chenglong Li, Ulyana Muñoz-Acuña, Djaja D. Soejarto, Ye Deng, Heebyung Chai, T E Chagwedera, Li Pan, Esperanza J. Carcache de Blanco, Chunhua Yuan, Jie Li, Hongshan Lai, A. Douglas Kinghorn
Sphenostylisins A–C (1–3), three complex dimeric compounds representing two novel carbon skeletons, along with an additional eight new compounds, sphenostylisins D–K (4–11), were isolated from the active chloroform-soluble extract of the root
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f91ed28b4500ac21e8bd026e1714ca
https://europepmc.org/articles/PMC3827909/
https://europepmc.org/articles/PMC3827909/
Autor:
Norman R. Farnsworth, T E Chagwedera, Ye Deng, Li Pan, A. D. Kinghorn, EJ Carcache de Blanco, Chunhua Yuan, HB Chai, Ulyana Muñoz-Acuña, DD Soejarto, Jie Li
Publikováno v:
Planta Medica. 79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e784b328cfbf36981ab8d05d0401db6
https://doi.org/10.1055/s-0033-1348771
https://doi.org/10.1055/s-0033-1348771
Autor:
Gloria L. Silva, D. B. M. Wickramaratne, J. M. Pezzuto, T E Chagwedera, Geoffrey A. Cordell, Norman R. Farnsworth, A. D. Kinghorn, HB Chai, Min You
Publikováno v:
Journal of Natural Products. 58:598-604
A known aporphine alkaloid, (-)-roemerine [1], isolated from the leaves of Annona senegalensis, was found to enhance the cytotoxic response mediated by vinblastine with multidrug-resistant KB-V1 cells. In the absence of vinblastine, no significant cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb2b55922de697906bfb71f9705e7ee
https://doi.org/10.1021/np50118a021
https://doi.org/10.1021/np50118a021
Autor:
Norman R. Farnsworth, Eun Kyoung Seo, T E Chagwedera, Gloria L. Silva, Heebyung Chai, A. D. Kinghorn, John M. Pezzuto, Geoffrey A. Cordell
Publikováno v:
ChemInform. 28
From the leaves of Monotes engleri, five prenylated flavanones were isolated as constituents that displayed cytotoxic activity against several human cancer cell lines. Three of these substances are novel, namely, 6-(1,1-dimethylallyl)naringenin, 6-(1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1549eed7326d6234d634f52abcdb1cab
https://doi.org/10.1002/chin.199738293
https://doi.org/10.1002/chin.199738293
Autor:
Qi Gao, T E Chagwedera, Heebyung Chai, John M. Pezzuto, Geoffrey A. Cordell, A. Douglas Kinghorn, Norman R. Farnsworth, Daniel Chávez
Publikováno v:
ChemInform. 32
Four novel stilbenes ( 1 – 4 ) were isolated from the root bark of Ekebergia benguelensis . The structures were established by spectroscopic methods including 2D NMR analysis. The structure of 1 , a new stilbene–coumarin hybrid representing a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c0d6c0a1c09ab0c6fd4baefb152fce
https://doi.org/10.1002/chin.200136227
https://doi.org/10.1002/chin.200136227
Autor:
Norman R. Farnsworth, A. D. Kinghorn, Geoffrey A. Cordell, John M. Pezzuto, Heebyung Chai, Eun Kyoung Seo, T E Chagwedera
Publikováno v:
Planta medica. 66(2)
A new coumarin, 5-(4-hydroxyphenethenyl)-4,7-dimethoxycoumarin (1) was isolated from the combined ethyl acetate extracts of the root bark, root wood and stem bark of Monotes engleri, and found to be cytotoxic against two cell lines in a human tumor p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9eccd0d9fd7ee2e130dcb3c07c0efe
https://pubmed.ncbi.nlm.nih.gov/10763599
https://pubmed.ncbi.nlm.nih.gov/10763599
Autor:
A. D. Kinghorn, Lori Kornberg, T E Chagwedera, Mansukh C. Wani, Fekadu Fullas, Norman R. Farnsworth, Monroe E. Wall
Publikováno v:
Journal of natural products. 59(2)
The rootwood of Aeschynomene mimosifolia Vatke (Leguminosae) has yielded a new neoflavonoid, mimosifoliol (1), and an unusual C16-styrylcycloheptenone derivative, mimosifolenone (2). The structures of these compounds were determined on the basis of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5383f208bd1ed19e26014d82bdd1b5
https://pubmed.ncbi.nlm.nih.gov/8991952
https://pubmed.ncbi.nlm.nih.gov/8991952
Autor:
Norman R. Farnsworth, Heebyung Chai, Lisa A. Shamon, Jeffrey M. Besterman, T E Chagwedera, A. Douglas Kinghorn, Geoffrey A. Cordell, John M. Pezzuto, k-Soo Lee
Publikováno v:
Chemico-biological interactions. 99(1-3)
Two structurally novel cytotoxic ent-kaurene diterpenoids, 13-methoxy-15-oxozoapatlin and 13-hydroxy-15-oxozoapatlin, were isolated from the root bark of Parinari curatellifolia, together with the known compound, 15-oxozoapatlin, on the basis of bioa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92c03e056fa65b8a0965add9ada033e
https://pubmed.ncbi.nlm.nih.gov/8620568
https://pubmed.ncbi.nlm.nih.gov/8620568
Autor:
M. C. Wani, Norman R. Farnsworth, Fekadu Fullas, Dan Brown, J. M. Pezzuto, T E Chagwedera, A. D. Kinghorn, Monroe E. Wall
Publikováno v:
Journal of natural products. 58(10)
A new polyacetylenic diepoxide compound, gummiferol [1] was isolated from the leaves of Adenia gummifera by KB cytotoxicity-guided fractionation. Compound 1 exhibited significant activity against the KB human cell line and a broad cytotoxic spectrum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba047672320bb6bfba1a63b1d692115
https://pubmed.ncbi.nlm.nih.gov/8676132
https://pubmed.ncbi.nlm.nih.gov/8676132